Systems Biology : Functional Strategies of Living Organisms - Konieczny, Leszek; Roterman-Konieczna, Irena; Spólnik, Paweł; SpringerLink (Online service) (Cham : Springer International Publishing : Imprint: Springer, 2014)
The Structure and Function of Living Organisms -- General physiochemical properties of biological structures -- Self-organization -- Hypothesis - Protein folding simulation hypothesis - late stage intermediate - role of water -- Energy in Biology - Demand and Use -- General principles of thermodynamics -- Biological energy sources - synthesis of water -- ATP synthesis -- Photosynthesis -- Direct and indirect exploitation of energy sources -- Energy conversion efficiency in biological processes -- Entropic effects -- Energy requirements of organisms -- Information - Its Role and Meaning in Organisms -- Information as a quantitative concept. - Reliability of information sources -- Types of information conveyed by DNA -- Information entropy and mechanisms assisting selection -- The role of information in interpreting pathological events -- Hypothesis - Protein folding early stage intermediate -- Regulation in Biological Systems -- The cell and the organism -- The principle and mechanism of automatic intracellular regulation -- Regulatory coupling between cells and organisms - hierarchical properties of regulation -- Regulatory mechanisms on the organism level -- Basic principles of regulation in biology -- Regulation levels -- Hypothesis - Proteome construction hypothesis -- Interrelationships in Organized Biological Systems -- The need of mutual relations in biological systems -- Cooperation and coordination -- The characteristics of process coordination in individual cells and organisms -- Mutual relationship between cells and the organism - activation and inhibition of enzymes (rapid effects) -- Mutual support between cells and the organism - interdependence related to gene expression (slow effects) -- Specialization of cell interrelationships -- Hypothesis - The criteria of life.
Keywords: Medicine; Systems biology; Cell biology; Bioinformatics; Biomedicine, general; Systems Biology; Cell Biology; Bioinformatics