Structure and Function of the Neural Cell Adhesion Molecule NCAM - Berezin, Vladimir; SpringerLink (Online service) (New York, NY : Springer New York : Imprint: Springer, 2010)
Structure and Ligands of NCAM -- Structural Biology of NCAM -- Extracellular Protein Interactions Mediated by the Neural Cell Adhesion Molecule, NCAM: Heterophilic Interactions Between NCAM and Cell Adhesion Molecules, Extracellular Matrix Proteins, and Viruses -- Intracelluar Ligands of NCAM -- NCAM and the FGF-Receptor -- The Role of ATP in the Regulation of NCAM Function -- NCAM and Polysialic Acid -- Polysialylation of NCAM -- Structural Basis for the Polysialylation of the Neural Cell Adhesion Molecule -- The Role of PSA-NCAM in Adult Neurogenesis -- Use of PSA-NCAM in Repair of the Central Nervous System -- NCAM-mediated Signal Transduction -- Signaling Pathways Involved in NCAM-Induced Neurite Outgrowth -- Role of the Growth-Associated Protein GAP-43 in NCAM-Mediated Neurite Outgrowth -- The Neural Cell Adhesion Molecule NCAM and Lipid Rafts -- The Neural Cell Adhesion Molecule and Epidermal Growth Factor Receptor: Signaling Crosstalk -- NCAM Metabolism -- Biosynthesis of NCAM -- Soluble NCAM -- NCAM, Synapses, Emotions, and Memory -- Role of NCAM in Spine Dynamics and Synaptogenesis -- NCAM in Long-Term Potentiation and Learning -- Role of NCAM in Emotion and Learning -- NCAM in Disease -- NCAM in Neuropsychiatric and Neurodegenerative Disorders -- Neural Cell Adhesion Molecule in Cancer: Expression and Mechanisms -- Pharmacology of NCAM: NCAM Mimetics -- NCAM Mimetic Peptides: An Update -- Synthetic NCAM-Derived Ligands of the Fibroblast Growth Factor Receptor -- Dendritic Spine and Synapse Morphological Alterations Induced by a Neural Cell Adhesion Molecule Mimetic -- Orthologs and Paralogs of NCAM -- Fasciclin II: The NCAM Ortholog in Drosophila melanogaster -- The Neural Cell Adhesion Molecule NCAM2/OCAM/RNCAM, a Close Relative to NCAM -- Conclusion -- Honoring Dr. Elisabeth Bock.
Keywords: Neurosciences; Human physiology; Neurobiology; Neurochemistry; Neurosciences; Human Physiology; Neurobiology; Neurochemistry