Single Nucleotide Polymorphisms : Methods and Protocols - Komar, Anton A.; SpringerLink (Online service) (Totowa, NJ : Humana Press : Imprint: Humana, 2009)
to Single Nucleotide Polymorphisms -- SNPs: Impact on Gene Function and Phenotype -- Silent (Synonymous) SNPs: Should We Care About Them? -- Bioinformatic Analysis of SNPs -- SNP Databases -- Mining SNPs from DNA Sequence Data; Computational Approaches to SNP Discovery and Analysis -- SNP Identification and Detection Strategies: Whole Genome Sequencing and Re-Sequencing -- Next-Generation Sequencing Methods: Impact of Sequencing Accuracy on SNP Discovery -- Scanning Probe and Nanopore DNA Sequencing: Core Techniques and Possibilities -- Pyrosequencing for SNP Genotyping -- Prescreening (Melting Based) Methods for SNP Discovery and Analysis -- Single Nucleotide Polymorphism Screening with Denaturing Gradient Gel Electrophoresis -- Temporal Temperature Gradient Electrophoresis for Detection of Single Nucleotide Polymorphisms -- Prescreening (Conformation Based) Methods for SNP Discovery and Analysis -- Zn(II)-Cyclen Polyacrylamide Gel Electrophoresis for SNP Detection -- Phosphate-Affinity Polyacrylamide Gel Electrophoresis for SNP Genotyping -- Estimation of SNP Allele Frequencies by SSCP Analysis of Pooled DNA -- Phenylethynylpyrene Excimer Forming Hybridization Probes for Fluorescence SNP Detection -- The Chemical Cleavage of Mismatch for the Detection of Mutations in Long DNA Fragments -- Mismatch Oxidation Assay: Detection of DNA Mutations Using a Standard UV/Vis Microplate Reader -- Towards High-Throughput Methods of SNP Genotyping -- High-Throughput Methods for SNP Genotyping -- High-Throughput SNP Genotyping: Combining Tag SNPs and Molecular Beacons -- SNP Genotyping by the 5?-Nuclease Reaction: Advances in High-Throughput Genotyping with Nonmodel Organisms -- The TaqMan Method for SNP Genotyping -- Qualitative and Quantitative Genotyping Using Single Base Primer Extension Coupled with Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MassARRAY®) -- SNP Detection Using Trityl Mass Tags -- Putting the Invader® Assay to Work: Laboratory Application and Data Management -- SNP Genotyping Using Multiplex Single Base Primer Extension Assays -- High-Throughput SNP Detection Based on PCR Amplification on Magnetic Nanoparticles Using Dual-Color Hybridization -- Other Methods -- Restriction Enzyme Analysis of PCR Products -- Allele-Specific PCR in SNP Genotyping -- Modified Multiple Primer Extension Method -- Detection of SNP by the Isothermal Smart Amplification Method.
Keywords: Human genetics; Cell biology; Medical genetics; Human Genetics; Cell Biology; Gene Function