Targeted Drug Strategies for Cancer and Inflammation - Jackman, Ann L.; Leamon, Christopher P.; SpringerLink (Online service) (New York, NY : Springer New York : Imprint: Springer, 2011)
Biological Role, Properties and Therapeutic Applications of the Reduced Folate Carrier (RFC-SLC19A1) and the Proton-Coupled Folate Transporter (PCFT-SLC46A1) -- Folate Receptors and Therapeutic Applications -- Hormonal Control of Folate Receptor Genes -- Folate Receptor Targeted Radionuclide Imaging Agents -- Folate receptor targeted thymidylate synthase inhibitors -- Discovery of novel antifolate inhibitors of de novo purine nucleotide biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier for cellular entry -- Folate-receptor targeted cancer chemotherapy -- Anti-FR antibody generation and engineering: development of new therapeutic tools -- Folate Receptor Positive Macrophages: Cellular Targets for Imaging and Therapy of Inflammatory and Autoimmune Diseases -- Targeting Activated Macrophages via a Functional Folate Receptor for Potential Treatment of Autoimmune/Inflammatory Disorders.-.
Keywords: Cancer research; Pharmacology; Cancer Research; Pharmacology/Toxicology.