Voltage Gated Sodium Channels - Ruben, Peter C.; SpringerLink (Online service) (Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2014)
Overview: biophysical properties and structure of sodium channels.- The voltage sensor module in sodium channels -- Slow inactivation of Na+ channels -- Regulation/modulation of sensory neuron sodium channels -- Ubiquitylation of voltage-gated sodium channels -- Probing gating mechanisms of sodium channel using pore blockers -- Animal toxins influence voltage-gated sodium channel function -- Voltage-sensor trapping toxins: Iso form-specific ligands for sodium channels -- Pharmacological insights and quirks of bacterial sodium channels -- The role of non-pore-forming β subunits in physiology and pathophysiology of voltage-gated sodium channels -- The role of late INa in development of cardiac arrhythmias -- Proton modulation of cardiac INa: A potential arrhythmogenic trigger -- Altered sodium channel gating as molecular basis for pain: Contribution of activation, inactivation and resurgent currents. .
Keywords: Pharmacology; Neurosciences; Cardiology; Cell membranes .; Proteins .; Pharmacology/Toxicology.; Neurosciences; Cardiology; Membrane Biology; Protein Structure