The Proteasome in Neurodegeneration
| Autor Corporativo: | |
|---|---|
| Otros Autores: | , |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
New York, NY :
Springer US : Imprint: Springer,
2006.
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| Edición: | 1st ed. 2006. |
| Materias: | |
| Acceso en línea: | https://doi.org/10.1007/0-387-28500-8 |
Tabla de Contenidos:
- Basic Aspects of Protein Degradation Through the Ubiquitin Proteasome System (UPS)
- Yeast Proteasome Structure and Biogenesis
- Ubiquitin-Proteasome System in the Central Nervous System
- Protein Aggregation, Inclusion Formation and Ups Function
- Protein Aggregation and the UPS: A Two-Way Street
- The Impact of Inclusion Formation on Cell Survival
- Inclusion Formation and Disolution Following Proteasomal Inhibition in Neuronal Cells
- Oxidative Stress and Ups Function
- The Proteasome: Source and a Target of Oxidative Stress?
- Inflammation as a Mediator of Oxidative Stress and UPS Dysfunction
- Proteasome and Neuronal Cell Death and Survival
- Role of the Ubiquitin Proteasome System During Neuronal Cell Death
- Pathways of Neuronal Cell Death Induced by Proteasomal Inhibition
- Models of Dysfunction of the UPS and the Proteasome
- Pharmacological and Molecular Models of Proteasomal Dysfunction
- The Gad Mouse: A Window Into UPS-Related Neurodegeneration and the Function of the Function of the Deubiquitinating Enzyme Uch-L1
- The UPS in Neurodegenerative Diseases and Aging
- Parkinson's Disease and Related Disorders
- Ubiquitination by Parkin - Implications in Parkinson's Disease
- The Ups in Neurodegenerative Diseases and Aging Huntington's Disease
- Frameshift Mutant Ubiquitin in Alzheimer's Disease and Other Neurodegenerative Disorders
- Motor Neuron Disease
- The Paradoxical Role of Proteasomes in Prion Disorders
- Aging and the Proteasome.