The p53 Tumor Suppressor Pathway and Cancer
| Autor Corporativo: | |
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| Otros Autores: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
New York, NY :
Springer US : Imprint: Springer,
2005.
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| Edición: | 1st ed. 2005. |
| Colección: | Protein Reviews ;
2 |
| Materias: | |
| Acceso en línea: | https://doi.org/10.1007/0-387-30127-5 |
Tabla de Contenidos:
- The p53 Network
- The Three-Dimensional Structure of p53
- Transcriptional Activation by p53: Mechanisms and Targeted Genes
- Transcriptional Repression by the p53 Tumor Suppressor Protein
- Posttranslational Modifications of p53: Upstream Signaling Pathways
- p53 in Human Cancer - Somatic and Inherited Mutations and Mutation-independent Mechanisms
- MDM2 and MDMX Regulators of p53 Activity
- p53 Family Members: p63 and p73
- The Oncogenic Activity of p53 Mutants
- Therapeutic Strategies Based on Pharmacological Modulation of p53 Pathway.