Protein Misfolding, Aggregation and Conformational Diseases Part B: Molecular Mechanisms of Conformational Diseases - Uversky, Vladimir N.; Fink, Anthony; SpringerLink (Online service) (New York, NY : Springer US : Imprint: Springer, 2007)
Altered Protein Structure and Enhanced Aggregation/Deposition -- The Pathogenesis of Alzheimer's Disease: General Overview -- Free Radicals, Metal Ions, and A? Aggregation and Neurotoxicity -- Progress in Understanding the Mechanisms of Neuronal Dysfunction and Degeneration in Parkinson's Disease -- ?-Synuclein Aggregation and Parkinson's Disease -- Cell Biology of ?-Synuclein: Implications in Parkinson's Disease and Other Lewy Body Diseases -- Pathogenesis of Prion Diseases -- Mammalian Prion Protein -- The Yeast Prion Proteins Sup35p and Ure2p -- Immunoglobulin Light Chain and Systemic Light-Chain Amyloidosis -- Pancreatic Islet Amyloid and Diabetes -- ?2-Microglobulin and Dialysis-Related Amyloidosis -- Serum Amyloid A and AA Amyloidosis -- Point Mutations and Enhanced Protein Deposition -- Transthyretin and the Transthyretin Amyloidoses -- Human Lysozyme -- Serpins and the Diversity of Conformational Diseases -- Altered Protein Structure and Impaired Function -- Human Copper-Zinc Superoxide Dismutase and Familial Amyotrophic Lateral Sclerosis -- Understanding the Effects of Cancer-Associated Mutations in the Tumor Suppressor Protein p53: Structural Consequences of Mutations and Possible Ways of Rescuing Oncogenic Mutants -- Changes in Supramolecular Structure -- Protein Aggregation in Muscle Fibers and Respective Neuromuscular Disorders -- Muscular Dystrophies and Protein Mutations -- The Functional Consequences of Dystrophin Deficiency in Skeletal Muscles -- Eye Lens Proteins and Cataracts -- Altered Protein Structure and Changes in Cellular/Nuclear Function -- Glutamine/Asparagine-Rich Regions in Proteins and Polyglutamine Diseases -- Mechanistic Insights into the Polyglutamine Ataxias -- Molecular Pathogenesis of the Polyglutamine Disease: Spinal and Bulbar Muscular Atrophy -- Post-Translational Modification and Protein Conformational Diseases -- Protein Glycation and Cataract: A Conformational Disease -- Defective Glycosylation and Muscular Dystrophies.
Keywords: Immunology; Cell biology; Immunology; Cell Biology