The Kinetochore: From Molecular Discoveries to Cancer Therapy - De Wulf, Peter; Earnshaw, William; SpringerLink (Online service) (New York, NY : Springer New York : Imprint: Springer, 2009)
Centromeres and Kinetochores: An Historical Perspective -- The Basics of Chromosome Segregation -- The Centromere -- Neocentromeres -- Human Artificial Centromeres: Assembly of Functional Centromeres on Human Artificial Chromosomes -- Kinetochore Composition, Formation, and Organization -- Evolution of Centromeres and Kinetochores: A Two-Part Fugue -- Mitotic Spindle Assembly Mechanisms -- Kinetochore-Microtubule Interactions -- Post-Translational Modifications that Regulate Kinetochore Activity -- The Role of the Kinetochore in Spindle Checkpoint Signaling -- Kinetochore Regulation of Anaphase and Cytokinesis -- Roles of Centromeres and Kinetochores in Meiosis -- The Kinetochore-Cancer Connection -- The Kinetochore as Target for Cancer Drug Development.
Keywords: Cancer research; Cell biology; Medical microbiology; Molecular biology; Human genetics; Virology; Cancer Research; Cell Biology; Medical Microbiology; Molecular Medicine; Human Genetics; Virology