Pharmacological Mechanisms in Alzheimer's Therapeutics - Cuello, A. Claudio; SpringerLink (Online service) (New York, NY : Springer New York : Imprint: Springer, 2007)
Overview of the Alzheimer's Disease Pathology and Potential Therapeutic Targets -- Trial Designs and Outcomes to Monitor Novel Therapeutics in Alzheimer's Disease -- The Pharmacological Treatment of Alzheimer's Disease with Cholinesterase Inhibitors and Memantine -- M1 Muscarinic Agonists: A Comprehensive Therapy Against Major Hallmarks of Alzheimer's Disease -- Cholinergic Neurodegeneration in Alzheimer's Disease: Basis for Nerve Growth Factor Therapy -- The Rationale for Glutamatergic Therapy in Alzheimer's Disease -- Secretases as Pharmacological Targets in Alzheimer's Disease -- ?-Secretase as a Target for Alzheimer's Disease -- The Rationale for an Immunological Approach to Alzheimer's Therapeutics -- Neuroinflammation, Alzheimer Disease, and Other Aging Disorders -- Nonsteroidal Anti-inflammatory Drugs (NSAIDs) and Derived A?42-Lowering Molecules for Treatment and Prevention of Alzheimer's Disease (AD) -- The Potential Application of Antioxidant Agents in Alzheimer Disease Therapeutics -- Apolipoprotein E: A Potent Gene-Based Therapeutic Target for the Treatment of Sporadic Alzheimer's Disease -- Tau Pathology as a Target in Alzheimer's Therapeutics -- Design of Inhibitors of Amyloid-? Misfolding and Aggregation for Alzheimer's Therapy -- Potential Applications of Glycosaminoglycan-Related Compounds in Alzheimer's Disease -- Multifunctional Neuroprotective Drugs for the Treatment of Alzheimer's Disease -- Interpreting Clinical Studies of Putative Therapeutics for Alzheimer's Disease: The Case of Statins and NSAIDs.
Keywords: Pharmacology; Pharmacology/Toxicology.