It's Great! Oops, No It Isn't Why Clinical Research Can't Guarantee The Right Medical Answers. - Gauch, Ronald; SpringerLink (Online service) (Dordrecht : Springer Netherlands : Imprint: Springer, 2009)
Medical Research Explained -- Medical Research - Searching for Answers -- The Case-Control Method - Looking Backwards -- The Cohort Study - Watchful Waiting -- The Clinical Trial -The Gold Standard -- Comparing the Methods - Qualitative Differences -- Understanding the Clinical Trial -- The Protocol - The Guiding Light -- The Control Group - Leveling the Playing Field -- Measurements - They'ever Exact -- Bias Control - A Closer Look at Blinding and Randomization -- Utility - Are Clinical Trial Results Useful? -- Research Discrimination - Inadequately Tested Populations -- Seven Deadly Flaws - The Clinical Trials' Achilles' Heel -- Tools of the Trade -- Statistics - Was the Finding Significant? -- Analysis Issues - A Lot of Choices -- Meta Analysis - An Alternative to Large Trials -- The Real World -- Research Results That Clashed - What's the Right Answer? -- Hormone Replacement Therapy - The Silver Bullet That Misfired -- Publishing - Getting the Word Out to Doctors -- The Public Forum - Sharing the News with the Public -- Product Development - Getting Discoveries to the Market -- Medical Innovations - Regulators, Resources and Results -- Science and Politics - A Troubling Mixture -- Research Misconduct - Irresistible Temptation -- Postmarketing Surveillance - An Imperfect System -- Regulatory Reform - Changes Needed -- Journey's End - A Call for Action.
Keywords: Medicine; Medicine .; Health; Public health; Statistics .; Epidemiology; Biomedicine, general; Popular Science in Medicine and Health; Medicine/Public Health, general; Public Health; Statistics for Life Sciences, Medicine, Health Sciences; Epidemiology