Solving Problems in Genetics - Kowles, Richard; SpringerLink (Online service) (New York, NY : Springer New York : Imprint: Springer, 2001)
1 Mendelism -- Basic Probability: Methods for Analyzing Mendelian Genetics -- Forked Line Method -- Mendel's Data -- Crosses Involving Three or More Gene Pairs -- Goodness of Fit Testing -- Subdividing Chi Square -- Gene Interaction -- Distinguishing Among Genetic Ratios -- Double Fertilization in Plants -- Additional Plant Genetics Considerations -- Problems -- Solutions -- Reference -- 2 Sex Determination and Sex Linkage -- General Aspects of Mating Systems -- XX/XY Chromosome System -- Sex Ratios -- Binomial Statistics -- Haploid-Diploid Sex Determination -- Sex Linkage -- Pedigrees -- Partial Sex-Linkage -- Problems -- Solutions -- 3 Chromosomes and Cell Division -- Chromosomes -- The Cell Cycle -- Further Analysis of the Cell Cycle -- Percent Labeled Mitoses Method -- Mitosis -- Meiosis -- Genetic Diversity -- C Values -- Problems -- Solutions -- 4 Linkage, Recombination, and Mapping -- Exceptions to Independent Assortment -- Recombination Values and Genetic Maps -- Three-Point Tests -- Mapping Concepts -- Recombination Calculated with F2 Data -- Haploid Genetics -- Tetrad Analysis -- Tetrad Analysis and Gene Mapping -- Problems -- Solutions -- Reference -- 5 Variations in Chromosome Number and Structure -- Types of Chromosome Variation -- Aneuploidy -- Polyploidy -- Deletions and Duplications -- Inversions -- Translocations -- Other Aberrations -- Problems -- Solutions -- 6 Quantitative Inheritance -- Continuous Variation -- Polygenes -- Estimating Number of Gene Pairs Involved in Quantitative Traits -- Variance -- Broad Sense Heritability -- Narrow Sense Heritability -- Heterosis -- Thresholds -- Mapping Quantitative Traits -- Problems -- Solutions -- Reference -- 7 Population Genetics -- Concept of Gene Pools -- Gene and Genotype Frequencies -- Hardy-Weinberg Principle -- Hardy-Weinberg Equilibrium -- Extensions of Hardy-Weinberg Relationships -- Genetic Drift -- Migration -- Mutation -- Selection -- A Statistical Approach to Change in a Population -- Nonrandom Mating -- Problems -- Solutions -- References -- 8 Gene Concepts -- One-Gene One-Enzyme -- Allelism -- Bacterial Genetics -- Bacteriophages -- Complementation -- Genetic Fine Structure Analysis in Bacteriophages -- Genetic Fine Structure Analysis in Other Organisms -- Problems -- Solutions -- References -- 9 Molecular Basis of Heredity -- Nucleic Acids -- Nearest Neighbor Frequency Analysis -- Central Dogma -- Semiconservative Mode of Replication -- Replication Forks and Okazaki Fragments -- Transcription -- Proteins -- Translation -- Genetic Code -- Regulation -- Operon Systems -- Mutation -- Mutation Detection -- Problems -- Solutions -- References -- 10 Non-Mendelian Inheritance -- Cytoplasmic Inheritance -- Male Sterility in Plants -- Maternal Effects -- Genomic Imprinting -- DNA Trinucleotide Repeats -- Meiotic Drive -- B Chromosomes -- Problems -- Solutions -- 11 Human Genetics -- Mendelian Inheritance in Humans -- Bias of Ascertainment -- Epidemiology and Pedigrees -- Linkage Analysis-Classical Approaches -- Physical Mapping -- Human Genome Project -- Population Genetics -- Testing Inheritance of a Single Allelic Pair in a Population -- Consanguinity -- Methods of Studying the Genetic Basis of Behavior in Humans -- Twin Studies and Concordance -- Problems -- Solutions -- References -- 12 Additional Genetic Analysis Using Statistics -- More Probability -- Permutations and Combinations -- The Binomial Distribution -- Poisson Distribution -- Contingency Tables-Test for Independence -- Problems -- Solutions.
Keywords: Human genetics; Cell biology; Human Genetics; Cell Biology