Microorganisms and Autoimmune Diseases - Friedman, Herman; Rose, Noel R.; Bendinelli, Mauro; SpringerLink (Online service) (New York, NY : Springer US : Imprint: Springer, 1996)
1. Bacterial Heat-Shock Proteins and Autoimmune Disease -- 1. Introduction -- 2. Peripheral Tolerance, Autoimmunity, and Environmental Bacteria -- 3. Experimental Models Support a Critical Role of Specific Immunity in Autoimmune Diseases -- 4. HSP60 and the Inhibition of Experimental Arthritis -- 5. Responses to Human HSP60 in Juvenile Chronic Arthritis -- 6. Lessons for the Development of Specific Immunotherapy in Autoimmunity -- References -- 2. Streptococci and Rheumatic Fever -- 1. Introduction -- 2. Historical Perspective -- 3. Clinical Features -- 4. Etiology: The Group A Streptococcus -- 5. Epidemiology and Host Susceptibility -- 6. Autoimmune Pathogenesis of Acute Rheumatic Fever -- 7. Animal Models of Rheumatic Heart Disease -- 8. Treatment and Prevention -- References -- 3. HLA-B27, Enteric Bacteria, and Ankylosing Spondylitis -- 1. Introduction -- 2. One- and Two-Gene Theories -- 3. Description of HLA-B27-Associated Disease Markers in the Pathogenesis of Ankylosing Spondylitis -- 4. Evidence for HLA-B27-Restricted Cytotoxic T Lymphocytes in the Pathogenesis of Ankylosing Spondylitis and Other Seronegative Arthropathies -- 5. Conclusions and Future Directions -- References -- 4. Triggering of Autoimmune Antibody Responses in Syphilis -- 1. Introduction -- 2. Overview of the Disease -- 3. Immune Complexes and Autoimmune Responses in Syphilis -- 4. Polyclonal B-Cell Activation -- 5. Idiotypic Networks -- 6. Molecular Mimicry -- 7. Concluding Remarks -- References -- 5. Viruses and Diabetes Mellitus -- 1. Introduction -- 2. Viruses and Autoimmune Diabetes -- 3. Interferon and Diabetes -- 4. Molecular Mimicry between Viruses and Beta-Cell Autoantigens -- 5. Transgenic Models of Virus-Induced Diabetes -- 6. Concluding Remarks -- References -- 6. The Role of Coxsackie B Viruses in the Pathogenesis of Type I Diabetes -- 1. Introduction -- 2. Epidemiological Studies -- 3. Difficulties Encountered in Epidemiological Studies on the Relationship between Coxsackie B Viral Infections and IDDM -- 4. Case Reports and in Vitro Studies on Human Islet Cells -- 5. Animal Studies -- 6. Mechanisms for Coxsackie B Virus-Induced Diabetes -- 7. Concluding Remarks -- References -- 7. Neuropathic Viruses and Autoimmunity -- 1. Neurotropic Infection -- 2. Virus Entry and Infection -- 3. Acute Infection -- 4. Persistent Viral Infections -- 5. Viral Complications of Immunosuppression -- 6. Parainfectious Syndromes -- 7. Discussion and Conclusions -- References -- 8. Postmeasles Encephalomyelitis -- 1. Introduction -- 2. Postmeasles Encephalomyelitis -- 3. Viral Induction of Autoimmune Disease -- 4. Autoimmune Destruction of Myelin -- 5. Additional Mechanisms of Viral Demyelination -- 6. Conclusion -- References -- 9. Epstein-Barr Virus and Autoimmunity -- 1. Introduction -- 2. The Epstein-Barr Virus -- 3. EBV-Related Diseases -- 4. Autoimmune Diseases Possibly Related to EBV -- 5. Autoimmunity in Infectious Mononucleosis -- 6. Conclusions -- References -- 10. Retroviruses and Autoimmunity -- 1. Introduction -- 2. Retroviruses and Autoimmune Disease -- 3. General Biology of Retroviruses -- 4. Classic Autoimmune Disorders and Associations with Retroviruses -- 5. Summary -- References -- 11. Autoimmunity in Chagas Disease -- 1. Introduction -- 2. Uncommon Molecular Features of Trypanosoma cruzi -- 3. The Paradox of Antigen-Driven Delayed-Type Hypersensitivity -- 4. The Paradox of the Severe Forms of Acute Chagas Disease in Santiago del Estero Infants -- 5. Downregulation of the Immune Response -- 6. Autoreactive Organ-Specific Delayed-Type Hypersensitivity and Autoantibodies -- References -- 12. Infection and Endocrine Autoimmunity -- 1. Introduction -- 2. The Potential Role of Infection in Autoimmunity -- 3. Autoimmune Thyroid Disease -- 4. Pituitary and Polyendocrine Autoimmunity -- 5. Conclusion -- References -- 13. Infection as a Precursor to Autoimmunity -- 1. Introduction -- 2. Myocarditis -- 3. An Animal Model of Myocarditis -- 4. Genetics of Autoimmune Myocarditis -- 5. The Role of Cytokines -- 6. Myosin as Autoantigen -- 7. Discussion -- References.
Keywords: Immunology; Medical microbiology; Plant science; Botany; Animal anatomy; Microbial ecology; Immunology; Medical Microbiology; Plant Sciences; Animal Anatomy / Morphology / Histology; Microbial Ecology