Mutation research Problems, results and perspectives - Auerbach, Charlotte; SpringerLink (Online service) (Boston, MA : Springer US : Imprint: Springer, 1976)
1 The history of mutation research -- 2 Classification of mutational changes at the chromosomal level -- 3 Classification of gene mutations -- 4 Reverse mutations. Suppressors -- 5 The classical X-ray work. I: Mutations. The target theory -- 6 The classical X-ray work II: Chromosome breaks and rearrangements. Do X-rays produce true gene mutations? -- 7 Direct and indirect action of X-rays. Radio-isotopes. Radiation-sterilized food -- 8 Repair of X-ray damage I: Repair of chromosome breaks -- 9 Repair of X-ray damage II: Repair of mutagenic lesions. Molecular action of X-rays. Sensitivity differences -- 10 Mutagenesis by ultraviolet and visible light I: Early work on macro-organisms -- 11 Mutagenesis by ultraviolet and visible light II: Methods of mutation research on microorganisms and mammalian cell cultures -- 12 Mutagenesis by ultraviolet and visible light II: Early work on micro-organisms -- 13 The molecular action of ultraviolet and visible light I: Photoproducts. Photorepair -- 14 The molecular action of ultraviolet and visible light II: Dark repair. Mechanisms of mutation induction -- 15 Chemical mutagens: alkylating agents. I: Genetical effects -- 16 Chemical mutagens: alkylating agents. II: Chemistry. Molecular analysis of mutants. Influence of cellular processes. Kinetics -- 17 Chemical mutagens: purines; base analogues; acridines; hydroxylamine; hydrazine; bisulphite. Reversions analysis -- 18 Nitrous acid. Other chemical mutagens -- 19 The relation between induced crossovers, rearrangements and mutations. The origin of complete (non-mosaic) mutations -- 20 Mutagen specificity -- 21 Spontaneous mutations -- 22 Instabilities -- 23 Applied mutation research -- Author Index.
Keywords: Animal genetics; Animal Genetics and Genomics