Natural Killer Cells Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Somanchi, Srinivas S. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Humana, 2016.
Edición:1st ed. 2016.
Colección:Methods in Molecular Biology, 1441
Materias:
Acceso en línea:https://doi.org/10.1007/978-1-4939-3684-7
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245 1 0 |a Natural Killer Cells  |b Methods and Protocols /  |c edited by Srinivas S. Somanchi. 
250 |a 1st ed. 2016. 
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300 |a XV, 365 p. 76 illus., 49 illus. in color.  |b online resource. 
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490 1 |a Methods in Molecular Biology,  |v 1441 
505 0 |a Tracking Effector and Memory NK Cells During MCMV Infection -- Application of Mass Cytometry (CyTOF) for Functional and Phenotypic Analysis of Natural Killer Cells -- Assessment of NK Cell Metabolism -- Genotyping Single Nucleotide Polymorphisms and Copy Number Variability of the FCGRs Expressed on NK Cells -- Measurement of Average Telomere Length in Ex Vivo Expanded Natural Killer Cells by Fluorescence In Situ Hybridization (FISH) -- In Vitro Assessment of Human Natural Killer Cell Migration and Invasion -- Microfluidic-Based Live-Cell Analysis of NK-Cell Migration In Vitro -- Microwell-Based Live Cell Imaging of NK Cell Dynamics to Assess Heterogeneity in Motility and Cytotoxic Response -- Assessment of Natural Killer Cell Cytotoxicity Using Image Cytometry Method -- Analysis of Intracellular Ca2+ Mobilization in Human NK Cell Subsets by Flow Cytometry -- Using NK Cell Lipid Raft Fractionation to Understand the Role of Lipid Rafts in NK Cell Receptor Signaling -- High- and Super-Resolution Microscopy Imaging of the NK Cell Immunological Synapse -- The Planar Lipid Bilayer System Serves as a Reductionist Approach for Studying NK Cell Immunological Synapses and their Functions -- Expansion of NK Cells Using Genetically Engineered K562 Feeder Cells -- Ex-Vivo Expansion of Human NK Cells Using K562 Engineered to Express Membrane Bound IL21 -- Large-Scale Culture and Genetic Modification of Human Natural Killer Cells for Cellular Therapy -- Gene Modification of Human Natural Killer Cells Using a Retroviral Vector -- Modification of Expanded NK Cells with Chimeric Antigen Receptor mRNA for Adoptive Cellular Therapy -- mRNA Transfection to Improve NK Cell Homing to Tumors -- In Vitro Generation of Human NK Cells Expressing Chimeric Antigen Receptor through Differentiation of Gene-Modified Hematopoietic Stem Cells -- Engineering Receptor Expression on Natural Killer Cells through Trogocytosis -- Electroporation of siRNA to Silence Gene Expression in Primary NK Cells -- Mouse Xenograft Model for Intraperitoneal Administration of NK Cell Immunotherapy for Ovarian Cancer -- Aerosol Delivery of Interleukin-2 in Combination with Adoptive Transfer of Natural Killer Cells for the Treatment of Lung Metastasis: Methodology and Effect -- Non-Invasive Imaging of Natural Killer Cell-Mediated Apoptosis in a Mouse Tumor Model -- Non-Invasive In Vivo Fluorescence Imaging of NK Cells in Pre-Clinical Models of Adoptive Immunotherapy -- In Vivo 19F-Magnetic Resonance Imaging of Adoptively Transferred NK Cells -- Generation of BiKEs and TriKEs to Improve NK Cell-Mediated Targeting of Tumor Cells -- Regulatory Considerations for NK Cells Used in Human Immunotherapy Applications. 
650 0 |a Immunology. 
650 1 4 |a Immunology. 
700 1 |a Somanchi, Srinivas S.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
856 4 0 |u https://doi.org/10.1007/978-1-4939-3684-7