Meningococcal Vaccines Methods and Protocols - Pollard, Andrew J.; Maiden, Martin C.J.; SpringerLink (Online service) (Totowa, NJ : Humana Press : Imprint: Humana, 2001)
Meningococcal Vaccines and Vaccine Developments -- Immune Response and Host-Pathogen Interactions -- Purification of Capsular Polysaccharide -- Protein-Polysaccharide Conjugation -- N-Propionylation -- Outer Membrane Protein Purification -- Outer Membrane Protein Vesicle Vaccines for Meningococcal Disease -- Methods for Manipulation of Transferrin-Binding Proteins -- Methods for the Preparation and Crystallization of Fab Fragments in Complex with Peptide Antigens Derived from N. meningitidis Outer Membrane Proteins -- Application of Optical Biosensor Techniques to the Characterization of PorA-Antibody Binding Kinetics -- Construction of porA Mutants -- Construction of LPS Mutants -- Recombinant Proteins in Vaccine Development -- Identification of Peptides that Mimic N. meningitidis LOS Epitopes Via the Use of Combinatorial Phage-Display Libraries -- Testing Meningococcal Vaccines for Mitogenicity and Superantigenicity -- Early Experiences with Nasal Vaccines against Meningococcal Disease -- Animal Models for Meningococcal Disease -- Determination of Antibody Responses to Meningococcal Antigens by ELISA -- Immunoblot Analysis of Sera from Patients and Vaccinees -- Serogroup B and C Serum Bactericidal Assays -- A Modified ELISA for Measurement of High-Avidity IgG Antibodies to Meningococcal Serogroup C Polysaccharide that Correlate with Bactericidal Titers -- Whole-Blood Model -- Antibody-Induced Opsonophagocytosis of Serogroup B Meningococci Measured by Flow Cytometry -- T-Cell Responses Against Meningococcal Antigens -- CD4 T-Cell Epitope Mapping -- Epitope Mapping -- Meningococcal Vaccine Trials -- The Introduction of Group C Conjugate Meningococcal Vaccine into the UK.
Keywords: Infectious diseases; Infectious Diseases