Tumor Suppressor Genes Volume 2: Regulation, Function, and Medicinal Applications - El-Deiry, Wafik S.; SpringerLink (Online service) (Totowa, NJ : Humana Press : Imprint: Humana, 2003)
Understanding the Function and Regulation of Tumor Suppressor Genes -- Utilizing NMR to Study the Structure of Growth-Inhibitory Proteins -- Generation and Application of Phospho-specific Antibodies for p53 and pRB -- Stability and Ubiquitination of the Tumor Suppressor Protein p53 -- Role of Tumor Suppressors in DNA Damage Response -- In Situ Hybridization in Cancer and Normal Tissue -- Genetic Strategies in Saccharomyces cerevisiae to Study Human Tumor Suppressor Genes -- Electrophoretic Mobility Shift Analysis of the DNA Binding of Tumor Suppressor Gene Products -- Analysis of Gene Promoter Regulation by Tumor Suppressor Genes -- DNA Footprinting -- Identification of DNA-Binding of Tumor Suppressor Genes by Chromatin Immunoprecipitation -- Co-immunoprecipitation of Tumor Suppressor Protein-Interacting Proteins -- Microarray Approaches for Analysis of Tumor Suppressor Gene Function -- Analysis of Tumor Suppressor Gene-Induced Senescence -- Yeast Two-Hybrid Screening as a Means of Deciphering Tumor Suppressor Pathways -- Somatic Cell Knockouts of Tumor Suppressor Genes -- Colony Growth Suppression by Tumor Suppressor Genes -- Flow Cytometric Analysis of Cell Cycle Control by Tumor Suppressor Genes -- Analysis of Cyclin-Dependent Kinase Activity -- Tumor Suppressor Gene-Inducible Cell Lines -- In Vitro Models of Early Neoplastic Transformation of Human Mammary Epithelial Cells -- Tumor Suppression Through Angiogenesis Inhibition -- Flow Cytometric Analysis of Tumor Suppressor Gene-Induced Apoptosis -- Functional Analysis of Tumor Suppressor Genes in Mice -- The Tissue Microenvironment as an Epigenetic Tumor Modifier -- Analyzing the Function of Tumor Suppressor Genes Using a Drosophila Model -- Assembling a Tumor Progression Model -- Conformation-Sensitive Gel Electrophoresis for Detecting BRCA1 Mutations -- Medicinal Applications of Tumor Suppessors -- Conversion Technology and Cancer Predispositions -- Discovering Novel Anticancer Drugs -- Targets in Apoptosis Signaling -- Tumor Deprivation of Oxygen and Tumor Suppressor Gene Function -- Hormonal and Differentiation Agents in Cancer Growth Suppression -- Regulation of NF-?B by Oncoproteins and Tumor Suppressor Proteins -- Blocking Survivin to Kill Cancer Cells -- Targeting the Mitochondria to Enhance Tumor Suppression -- Novel Approaches to Screen for Anticancer Drugs Using Saccharomyces cerevisiae -- Tumor Suppressor Gene Therapy -- Therapeutic Strategies Using Inhibitors of Angiogenesis -- Isolation of p53 Inhibitors by Screening Chemical Libraries in Cell-Based Readout System.
Keywords: Oncology .; Oncology