Transgenic Mouse Methods and Protocols - Hofker, Marten H.; van Deursen, Jan.; SpringerLink (Online service) (Totowa, NJ : Humana Press : Imprint: Humana, 2002)
Introduction: The Use of Transgenic Mice in Biomedical Research -- Genetic Modification of the Mouse -- In Vitro Fertilization/Cryopreservation -- Transgene Design -- Generating Conditional Mouse Mutants via Tetracycline-Controlled Gene Expression -- Manipulating Large Insert Clones for Transgenesis -- Reporter Molecules in Genetically Engineered Mice -- Gene Targeting in Mouse Embryonic Stem Cells -- Conditional Knockout Mice -- Knockin Approaches -- Aggregation of Embryos and Embryonic Stem Cells -- Andenovirus-Mediated Gene Transfer -- Random ENU Mutagenesis -- Autopsy and Histologic Analysis of the Transgenic Mouse -- Bone Marrow Transplantations to Study Gene Function in Hematopoietic Cells -- Quantification of Atherosclerosis in Mice -- Genetically Modified Mice in Cancer Research -- Neuropathobiology in Transgenic Mice.
Keywords: Cell biology; Cell Biology