Opiate Receptors and Antagonists From Bench to Clinic - Dean, Reginald; Bilsky, Edward J.; Negus, S. Stevens; SpringerLink (Online service) (Totowa, NJ : Humana Press : Imprint: Humana, 2009)
Opioid Receptors -- Ultra-Low-Dose Opioid Antagonists Enhance Opioid Analgesia and Reduce Tolerance -- Upregulation of Opioid Receptors -- Imaging Human Brain Opioid Receptors: Applications to Substance Use Disorders -- Opioid Receptor Antagonist-Mediated Signaling in the Immune System -- Opioid Antagonists: Chemistry and Pharmacology -- The Chemistry and Pharmacology of ?-Opioid Antagonists -- Medicinal Chemistry of Kappa Opioid Receptor Antagonists -- The Chemistry and Pharmacology of Delta Opioid Antagonists -- Novel Opioid Antagonists with Mixed/Dual Selectivity -- Experimental Utility and Clinical Potential of Irreversible Opioid Antagonists -- Methylnaltrexone: A Peripherally Acting Opioid Antagonist -- Substance Abuse -- Opioid Antagonist Effects in Animal Models Related to Opioid Abuse: Drug Discrimination and Drug Self-Administration -- Naltrexone for Initiation and Maintenance of Opiate Abstinence -- Ultra-Low-Dose Naltrexone Decreases Dependence and Addictive Properties of Opioids -- Can a Combination Formulation Containing a Neutral Opiate Antagonist Decrease the Abuse of ?-Agonist Opiates -- Effects of Opioid Antagonists on the Abuse-Related Effects of Psychomotor Stimulants and Nicotine -- Potential Use of Opioid Antagonists in the Treatment of Marijuana Abuse and Dependence -- Naltrexone in Smoking Cessation: A Review of the Literature and Future Directions -- Alcohol and Ingestive Behaviors -- Opioid Antagonists and Ethanol's Ability to Reinforce Intake of Alcoholic Beverages: Preclinical Studies -- Clinical Use of Opioid Antagonists in the Treatment of Alcohol Dependence -- Preclinical Effects of Opioid Antagonists on Feeding and Appetite -- CNS Opiate Systems and Eating Disorders -- Behavioral Disorders -- Potential Utility of Kappa Ligands in the Treatment of Mood Disorders -- Opioid Antagonists in the Treatment of Pathological Gambling and Kleptomania -- Efficacy of Opioid Antagonists in Attentuating Self-Injurious Behavior -- Pharmacotherapeutic Effects of Opioid Antagonists in Alcohol-Abusing Patients with Schizophrenia -- Medical Indications -- Current Issues in the Use of Opioid Antagonists (Naltrexone for Opiate Abuse: A Re-Educational Tool as Well as an Effective Drug) -- Emergency Room Use of Opioid Antagonists in Drug Intoxication and Overdose -- Kappa-Opioid Antagonists as Pruritogenic Agents -- Clinical Effect of Opioid Antagonists on Clinical Pruritus -- Effects of Opioid Antagonists on l-DOPA-Induced Dyskinesia in Parkinson's Disease -- Endocrine Effects of Opioid Antagonists -- Opioid Antagonists in Traumatic Shock: Animal and Human Studies -- The Efficacy of Opioid Antagonists Against Heatstroke-Induced Ischemia and Injury in Rats -- A Review of the Opioid System in Cancer Patients and Preliminary Results of Opioid Antagonists in the Treatment of Human Neoplasms -- Nonclinical Pharmacology of VIVITROL®: A Monthly Injectable Naltrexone for the Treatment of Alcohol Dependence -- The Development of Sustained-Release Naltrexone and Clinical Use in Treating Opiate Dependence -- The Development of ProNeura Technology for the Treatment of Addictions -- Development of Opioid Transdermal Delivery Systems -- Intranasal Naloxone for Treatment of Opioid Overdose.
Keywords: Pharmacology; Pharmacology/Toxicology.