New Antibiotic Targets - Champney, W. Scott; SpringerLink (Online service) (Totowa, NJ : Humana Press : Imprint: Humana, 2008)
Biocomputational Strategies for Microbial Drug Target Identification -- Methods to Assay Inhibitors of DNA Gyrase and Topoisomerase IV Activities -- A Method to Assay Inhibitors of DNA Polymerase IIIC Activity -- Methods to Identify and Characterize Inhibitors of Bacterial RNA Polymerase -- Methods to Assay Inhibitors of tRNA Synthetase Activity -- Three Methods to Assay Inhibitors of Ribosomal Subunit Assembly -- Inhibition ofChaperone-Dependent Bacterial Ribosome Biogenesis -- Assays for the Identification of Inhibitors Targeting Specific Translational Steps -- SPARK: A New Peptidyl Transferase Activity Assay -- High-Throughput Screening of Peptide Deformylase Inhibitors -- A Method to Assay Penicillin-Binding Proteins -- A Method to Assay Inhibitors of Lipopolysaccharide Synthesis -- Methods for Assessing the Structure and Function of Cationic Antimicrobial Peptides -- Flow Cytometry of Bacterial Membrane Potential and Permeability -- Bacterial Efflux Pump Inhibitors -- Mycobacterium tuberculosis ?-Ketoacyl Acyl Carrier Protein Synthase III (mtFabH) Assay: Principles and Method -- Screening for Compounds That Affect the Interaction Between Bacterial Two-Component Signal Transduction Response Regulator Protein and Cognate Promoter DNA -- The Activity of rRNA Resistance Methyltransferases Assessed by MALDI Mass Spectrometry -- Assays for ?-Lactamase Activity and Inhibition -- Studies of Enzymes That Cause Resistance to Aminoglycosides Antibiotics.
Keywords: Infectious diseases; Immunology; Molecular biology; Virology; Infectious Diseases; Immunology; Molecular Medicine; Virology