How to Overcome the Antibiotic Crisis Facts, Challenges, Technologies and Future Perspectives - Stadler, Marc.; Dersch, Petra; SpringerLink (Online service) (Cham : Springer International Publishing : Imprint: Springer, 2016)
Tackling threats and future problems of multidrug-resistant bacteria.-Emergence and spread of antimicrobial resistance: recent insights from bacterial population genomics -- Epidemiology of Staphylococcus aureus nasal carriage patterns in the community -- Diagnostics and resistance profiling of bacterial pathogens -- Use of antibiotics and antimicrobial resistance in veterinary medicine as exemplified by the swine pathogen Streptococcus suis.-Antibiotics and the intestinal microbiome: individual responses, resilience of the ecosystem and the susceptibility to infections -- Anti-virulence strategies to target bacterial infections -- Strategies to block bacterial pathogenesis by interference with motility and chemotaxis -- New horizons in the development of novel needle-free immunization strategies to increase vaccination efficacy -- History of antibiotics research -- Actinobacteria and Myxobacteria - Two of the most important bacterial resources for novel antibiotics -- Exploitation of fungal biodiversity for discovery of novel antibiotics -- Strategies for the discovery and development of new antibiotics from natural products: Three Case Studies -- New structural templates for clinically validated and novel targets in antimicrobial drug research and development -- Synthesis of antibiotics -- Antibiotics clinical development and pipeline -- Anti-infectives in drug delivery-overcoming the Gram-negative bacterial cell envelope.
Keywords: Medical microbiology; Infectious diseases; Bacteriology; Pharmacology; Medicinal chemistry; Veterinary medicine; Medical Microbiology; Infectious Diseases; Bacteriology; Pharmacology/Toxicology.; Medicinal Chemistry; Veterinary Medicine/Veterinary Science