Molecular Chaperones in Health and Disease - Gaestel, Matthias; SpringerLink (Online service) (Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2006)
Chaperones in Preventing Protein Denaturation in Living Cells and Protecting Against Cellular Stress -- Feedback Regulation of the Heat Shock Response -- Protein Folding in the Endoplasmic Reticulum and the Unfolded Protein Response -- Molecular Chaperones in Signal Transduction -- Chaperoning of Glucocorticoid Receptors -- Heat Shock Response: Lessons from Mouse Knockouts -- HSFs in Development -- Heat Shock Proteins: Endogenous Modulators of Apoptotic Cell Death -- Protein Aggregation as a Cause for Disease -- The Role of Chaperones in Parkinson's Disease and Prion Diseases -- Chaperoning Oncogenes: Hsp90 as a Target of Geldanamycin -- Heat Shock Proteins in Immunity -- Molecular Chaperones and Cancer Immunotherapy -- Hsp90 Inhibitors in the Clinic -- Pharmacological Targeting of Catalyzed Protein Folding: The Example of Peptide Bond cis/trans Isomerases -- Chemical Chaperones: Mechanisms of Action and Potential Use -- Pharmacological Modulation of the Heat Shock Response.
Keywords: Biochemistry; Pharmacology; Medical biochemistry; Cell biology; Biochemistry, general; Pharmacology/Toxicology.; Medical Biochemistry; Cell Biology