Telomeres and Telomerase in Aging, Disease, and Cancer Molecular Mechanisms of Adult Stem Cell Ageing - Rudolph, K. Lenhard; SpringerLink (Online service) (Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2008)
Telomere Shortening and Ageing -- Cellular versus Organismal Aging -- Telomere-Induced Senescence of Primary Cells -- Telomeres, Senescence, Oxidative Stress, and Heterogeneity -- Initiation of Genomic Instability, Cellular Senescence, and Organismal Aging by Dysfunctional Telomeres -- Telomerase Mutations and Premature Ageing in Humans -- Telomerase, Telomeres, and Stem Cell Aging -- Mechanisms of Stem Cell Ageing -- Senescence Signatures of Human Hematopoietic Stem Cells -- Telomere Shortening Induces Cell Intrinsic Checkpoints and Environmental Alterations Limiting Adult Stem Cell Function -- p16INK4a and Stem Cell Ageing: A Telomere-Independent Process? -- Telomerase as a Potential Regulator of Tissue Progenitor Cells -- Telomeres, DNA Damage and Cancer -- Telomere Shortening and Telomerase Activation during Cancer Formation -- Telomere Binding Proteins and Disease -- Therapeutic Targets -- Targeting Telomerase: Therapeutic Options for Cancer Treatment -- Werner Syndrome, Telomeres, and Stress Signaling: Implications for Future Therapies?.
Keywords: Human genetics; Biochemistry; Cell biology; Cancer research; Human Genetics; Biochemistry, general; Cell Biology; Cancer Research