The Selection of Doses in Chronic Toxicity/Carcinogenicity Studies Age-Associated (Geriatric) Pathology: Its Impact on Long-Term Toxicity Studies - Grice, H.C.; SpringerLink (Online service) (Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 1984)
The Selection of Doses in Chronic Toxicity/Carcinogenicity Studies -- I. Introduction -- II. Factors Relating to the Dose Selection -- III. Principles for Dose Selection -- IV. Evaluation and Interpretation of Experimental Findings -- V. Recommendations for Future Research on Dose Selection -- VI. Summary -- VII. Glossary of Terms - As They Pertain to Toxicology -- VIII. References -- Age-Associated (Geriatric) Pathology: Its Impact on Long-Term Toxicity Studies -- I. Introduction -- II. Types of Long-Term Tests -- III. Factors Related to the Aging Process that Influence the Design and Conduct of Long-Term Rodent Studies -- IV. Age-Associated Diseases: How They Complicate Long-Term Toxicity Studies -- V. Effect of Aging on Drug Metabolism -- VI. Duration of Long-Term Studies -- VII. Cost of Conducting Toxicity Studies with Durations of 18, 24, or 30 Months -- VIII. Conclusions -- IX. Areas in Need of Future Research -- X. Summary -- XI. References.
Keywords: Pharmacology; Oncology .; Pharmacy; Pharmacology/Toxicology.; Oncology; Pharmacy