Interpretation and Extrapolation of Chemical and Biological Carcinogenicity Data to Establish Human Safety Standards The Use of Short-Term Tests for Mutagenicity and Carcinogenicity in Chemical Hazard Evaluation /
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| Format: | eBook |
| Language: | English |
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Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
1984.
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| Edition: | 1st ed. 1984. |
| Series: | Current Issues in Toxicology,
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| Online Access: | https://doi.org/10.1007/978-3-642-49371-3 |
Table of Contents:
- Interpretation and Extrapolation of Chemical and Biological Data on Carcinogens to Establish Human Safety Standards
- I. Introduction
- II. Chronic Toxicity/Carcinogenicity Bioassay
- III. Short-Term Tests
- IV. Pharmacokinetics and Metabolism
- V. Synergism and Antagonism
- VI. Mechanisms of Action
- VII. Systematic Analysis of the Chemical and Biological Properties of Carcinogens
- VIII. Establishing Human Exposure Guidelines
- IX. Appendix: Profiles of Selected Compounds
- X. References
- The Use of Short-Term Tests for Mutagenicity and Carcinogenicity in Chemical Hazard Evaluation
- I. Introduction
- II. Development of Test Strategies
- III. Review of Organization Guidelines
- IV. Future Developments
- V. Batteries of Short-Term Tests
- VI. Approaches to the Interpretation of Short-Term Test Results
- VII. Conclusions
- VIII. References.