Creatine Kinase Isoenzymes Pathophysiology and Clinical Application - Lang, Hermann; SpringerLink (Online service) (Berlin, Heidelberg : Springer Berlin Heidelberg, 1981)
1 Introduction -- 1.1 Creatine Kinase in Muscular Metabolism -- 1.2 Creatine Kinase in Clinical Chemistry -- 1.3 Creatine Kinase Isoenzymes -- 1.4 Scope and Summary of this Book -- 2 Creatine Kinase Isoenzymes -- 2.1 The Cytoplasmic Isoenzymes from Human Tissues -- 2.2 The Mitochondrial Isoenzyme from Human Heart Muscle -- 3 Methods for Differentiation and Quantitation of Creatine Kinase Isoenzymes -- 3.1 Methods for Determination of Creatine Kinase Activity -- 3.2 Differentiation of Isoenzymes by Non Immunological Methods. -- 3.3 Measurement of Isoenzyme Activity by Immunological Methods. -- 3.4 Experimental Comparison of Methods for Differentiation of Isoenzymes -- 3.5 Measurement of Isoenzyme Concentration by Immunoassay. -- 4 Tissue Specific and Subcellular Distribution of Creatine Kinase Isoenzymes -- 4.1 Tissue Specific Distribution -- 4.2 Subcellular Distribution -- 4.3 Ontogeny -- 5 Clinical Results: Myocardium -- 5.1 Myocardial Infarction -- 5.2 Infarct Size Estimation from Serial Analyses of CK and Isoenzyme Activity. -- 5.3 Perioperative Infarction -- 5.4 Complications, Differential Diagnosis, and Diagnostic/ Therapeutic Procedures Associated with Myocardial Infarction. -- 5.5 Heart Failure and Inflammation. -- 6 Clinical Results: Skeletal Muscle -- 6.1 Direct Skeletal Muscle Damage. -- 6.2 Muscular Dystrophies. -- 6.3 Hypothyroidism. -- 6.4 Various Muscular Diseases. -- 6.5 Collagen Diseases. -- 7 Clinical Results: Central Nervous System -- 7.1 Cerebral Diseases. -- 7.2 Acute Psychosis. -- 8 Clinical Results: Gastrointestinal Tract, Liver, and Pancreas. -- 8.1 Gastrointestinal Tract Diseases -- 8.2 Liver Diseases -- 8.3 Pancreatic Diseases -- 9 Clinical Results: Kidney and Urogenital Tract. -- 9.1 Renal Diseases -- 9.2 Prostatic Carcinoma -- 10 Clinical Results: Intoxication -- 10.1 Exogenous Intoxication. -- 10.2 Alcoholism. -- 11 Clinical Results: Perinatal Period. -- 11.1 Enzymes in Pregnancy -- 11.2 Myometrium and Placenta -- 11.3 Maternal Serum During Pregnancy, Labor, and After Delivery -- 11.4 Cord Blood -- 11.5 Discussion -- 11.6 Summary -- 12 The Creatine Kinase 242 BB Isoenzyme. -- 12.1 Distribution ofCK-BB in Human Tissues -- 12.2 Problems in Evaluation of Published Data -- 12.3 Serum CK-BB Activity -- 12.4 CK-BB in Cerebrospinal Fluid -- 12.5 "Idiopathic" and "Macro" Serum CK-BB -- 12.6 Genetic Variants -- 12.7 Summary -- References -- List of Abbreviations.
Keywords: Human physiology; Biochemistry; Pathology; Human Physiology; Biochemistry, general; Pathology