Mouse Liver Tumors Relevance to Human Cancer Risk Symposium of the European Society ofToxicology Held in Rome, February 2-5, 1986 - Chambers, Philip L.; Henschler, Dietrich; Oesch, Franz; SpringerLink (Online service) (Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 1987)
The Mouse in Safety Evaluation -- Liver Lesions in B6C3F1 Mice: The National Toxicology Program, Experience and Position -- Biology and Functional Properties of Mouse Liver Nodules -- Invasiveness, Metastasis, and Transplantability of Mouse Liver Nodules -- Xenobiotic-Induced Peroxisome Proliferation: Role of Tissue Specificity and Species Differences in Response in the Evaluation of the Implications for Human Health -- The Role of Necrosis in Hepatocellular Proliferation and Liver Tumors -- Biological Markers Characterizing the Development of Preneoplastic and Neoplastic Lesions in Rodent Liver -- Relationship Among the Histochemically Distinguishable Early Lesions in Multistep-Multistage Hepatocarcinogenesis -- The Histopathology and Biochemistry of Phenobarbitone-Induced Liver Nodules in C3H Mice 95 -- Molecular Basis -- Species Differences in Enzymes Controlling Reactive Epoxides -- Species Differences of Glucuronidation and Sulfation in Relation to Hepatocarcinogenesis -- Glutathione S-Transferase Subunits in the Mouse and Their Catalytic Activities Towards Reactive Electrophiles -- Species Differences in Biotransformation of and Peroxisome Proliferation due to Trichloroethylene -- The Distribution of Carcinogen Metabolizing Enzymes in the Mouse Liver: Comparison of Parenchymal and Non-Parenchymal Cell Populations -- Investigations on the Mechanism of Liver Tumour Induction by Peroxisome Proliferators -- DNA Damage and Repair in Mouse Liver -- Individual Differences in DNA Repair Capacities in Man -- Variables Influencing DNA-Binding in Mouse Liver -- Pharmacokinetic Factors and Their Implication in the Induction of Mouse Liver Tumors by Halogenated Hydrocarbons -- Comparative Study on the Indirect Methylation of Liver DNA Guanine by the 1-Carbon Pool in Hepatotoxicity -- Activation of a Cellular Proto-Oncogene in Spontaneous Liver Tumor Tissue of B6C3F1 Mouse -- Modifying Factors -- Nutritional and Dietary Influences on Liver Tumorigenesis in Mice and Rats -- Anatomy, Function and Aging in the Mouse Liver -- Sex Hormones and Neoplasia: Liver Tumors in Rodents -- Sex Hormones and Neoplasia: Genotoxic Effects in Short Term Assays -- Mouse and Human Liver Tumors -- Pathogenesis of Experimental Liver Cancer Comparison with Humans -- Author Index.
Keywords: Pharmacology; Oncology .; Pharmacy; Pharmacology/Toxicology.; Oncology; Pharmacy