Drug Research and Drug Development in the 21st Century Science and Ethics - Wolff, H.P.; Fleckenstein, A.; Philipp, Egon O.; SpringerLink (Online service) (Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 1989)
History and Philosophy of Bayer Pharmaceutical Research -- Science, Responsibility, and Society -- Opening Remarks -- Message of Greeting -- I. Unresolved Problems of Chronic Diseases -- Demographic and Epidemiologic Trends Today -- Atherosclerosis and Coronary Heart Disease -- Rheumatoid Arthritis: A Modell of Chronic Inflammation -- Alzheimer's Disease -- Obstructive Lung Disease -- Biological Approaches to Cancer Therapy -- Challenges and Obstacles hi Clinical Evaluations of Therapy -- Problems, Pitfalls, and Opportunities in Long-term Randomized Trials -- The Impact of Clinical Trials on Clinical Practice -- Panel Discussion I: Cost Effectiveness of Drug Development and Health Economics -- II. Advanced Technologies, Scientific Achievements -- Receptors and Messengers -- Low Density Lipoproteins and Hypercholesterolemia -- Leukotrienes in Airways and Blood Vessels -- Drug Design -- Opening Remarks -- Thoughts About Gene Regulation and Mammalian Development -- Protein Crystallography and Drug Design -- Applying Engineering Principles to the Design of Cellular Biology -- Analytical Pathophysiology and Biochemistry -- Opening Remarks -- Neurotransmitters in the Brain -- Mechanisms of Cancer Metastasis -- Panel Discussion II: Objectives of Basic Research and Predictive Value Preclinical Testing -- The Patient as a Subject to Medical Research -- Ethics of Drug Research and Drug Development -- The Functions of Ethical Committees -- Reduction of Risk to Patients Through Optimized Planning of Clinical Drug Development -- The Quality of Life of Hypertensive Patients in Long-term Studies -- Panel Discussion III: Who is Concerned with Patient Welfare in Research? -- Concluding Remarks.
Keywords: Pharmacology; Cardiology; Neurology .; Allergy; Immunology; Pharmacy; Pharmacology/Toxicology.; Cardiology; Neurology; Allergology; Immunology; Pharmacy