The Enigma of Slow Viruses Facts and Artefacts /
| Main Author: | |
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| Corporate Author: | |
| Format: | eBook |
| Language: | English |
| Published: |
Vienna :
Springer Vienna : Imprint: Springer,
1993.
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| Edition: | 1st ed. 1993. |
| Series: | Archives of Virology. Supplementa,
6 |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/978-3-7091-9270-2 |
Table of Contents:
- 1. Introduction: subacute spongiform virus encephalopathies from the perspective of a neuroscientist
- 2. The molecular biology of the slow viruses
- 2.1. The search for the virus-specific nucleic acid
- 2.2. The prion protein
- 2.3. The structure of the gene encoding PrP 33-35 (Prn-p) in different species
- 2.4. The models of slow viruses
- 3. The pathogenesis of slow virus infection
- 3.1. The general sequence of the pathogenetic events
- 3.2. The role of the spleen
- 3.3. The role of the spleen in neuroinvasion
- 3.4. The role of viremia
- 3.5. The role of macrophages in scrapie infection
- 3.6. The neural spread of infectivity from the spleen to the central nervous system
- 3.7. The neural spread of infectivity within the central nervous system
- 3.8. Biochemistry and histochemistry of slow virus infections
- 4. Neuropathology of slow virus diseases Ill
- 4.1. Natural scrapie
- 4.2. Kuru
- 4.3. Creutzfeldt-Jakob disease (CJD)
- 4.4. Elements of neuropathology of slow virus disorders
- 5. Final conclusions
- Addendum
- References.