Systems Biological Approaches in Infectious Diseases - Boshoff, Helena I.; Barry, Clifton E.; SpringerLink (Online service) (Basel : Birkhäuser Basel : Imprint: Birkhäuser, 2007)
Systems biology and its impact on anti-infective drug development -- Applications of transcriptional profiling in antibiotics discovery and development -- Chemical genetics: An evolving toolbox for target identification and lead optimization -- Proteomic profiling of cellular stresses in Bacillus subtilis reveals cellular networks and assists in elucidating antibiotic mechanisms of action -- Elucidating the mode-of-action of compounds from metabolite profiling studies -- A subsystems-based approach to the identification of drug targets in bacterial pathogens -- Metabolic control analysis to identify optimal drug targets -- The protein network as a tool for finding novel drug targets -- Toxicogenomics applied to predictive and exploratory toxicology for the safety assessment of new chemical entities: a long road with deep potholes -- Biological robustness in complex host-pathogen systems -- Toward whole cell modeling and simulation: Comprehensive functional genomics through the constraint-based approach -- Genomics of host-pathogen interactions.
Keywords: Molecular biology; Molecular Medicine