Molecular, Clinical and Environmental Toxicology Volume 1: Molecular Toxicology - Luch, Andreas; SpringerLink (Online service) (Basel : Birkhäuser Basel : Imprint: Birkhäuser, 2009)
Historical milestones and discoveries that shaped the toxicology sciences -- Physiologically based toxicokinetic models and their application in human exposure and internal dose assessment -- The role of biotransformation and bioactivation in toxicity -- Genotoxicity: damage to DNA and its consequences -- Role of DNA repair in the protection against genotoxic stress -- On the impact of the molecule structure in chemical carcinogenesis -- Chemical induced alterations in p53 signaling -- Molecular pathways involved in cell death after chemically induced DNA damage -- The aryl hydrocarbon receptor at the crossroads of multiple signaling pathways -- Mapping the epigenome - impact for toxicology -- Receptors mediating toxicity and their involvement in endocrine disruption -- Toxicogenomics: transcription profiling for toxicology assessment -- The role of toxicoproteomics in assessing organ specific toxicity -- High-throughput screening for analysis of in vitro toxicity.
Keywords: Pharmacology; Mathematical physics; Pharmacology/Toxicology.; Mathematical Physics