Bone Metastases : A translational and Clinical Approach /

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Vassiliou, Vassilios. (Editor), Chow, Edward. (Editor), Kardamakis, Dimitrios. (Editor)
Format: eBook
Language:English
Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2014.
Edition:2nd ed. 2014.
Series:Cancer Metastasis - Biology and Treatment, 21
Subjects:
Table of Contents:
  • Preface. I Fundamental Concepts
  • Pathophysiology of metastatic bone disease
  • Bone metastases: epidemiology, clinical picture, SREs and prognosis
  • Pain in bone metastases: types and mechanisms. II Investigations Of Bone Metastases
  • Radiological evaluations: radiography, CT, MRI.- Nuclear medicine imaging modalities: bone scintigraphy, PET-CT, SPECT.- Bone turnover markers
  • New omics approaches for bone metastases. III Therapeutic Management.- Analgesic treatment for bone mets
  • Radiotherapy: external beam and radio-surgery
  • Radionuclide therapy
  • Bisphosphonates
  • New targeted therapies for bone metastases
  • Chemotherapy and hormone therapy
  • HIFU/Radioablation
  • Neuropathic bone metastases
  • Spinal cord compression and cauda equina compression
  • Pathological and impending fracture
  • Re-irradiation
  • Bone metastases in elderly patients
  • Management of metastatic bone disease in the elderly with bisphosphonates and RANKL inhibitors: effectiveness and safety. IV Assesment of Therapeutic Response
  • Radiological and nuclear medicine imaging modalities.- Clinical assessment measures
  • Outcome measures in bone metastases clinical trials
  • Quality of life in patients suffering from metastatic skeletal disease. V Cost of Managing Metastatic Bone Disease
  • Cost effectiveness of treatment modalities for bone metastases
  • Index.