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03088nam a22003375i 4500 |
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20210204135637.0 |
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cr nn 008mamaa |
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100825s2010 xxu| s |||| 0|eng d |
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|a 9781607617594
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| 024 |
7 |
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|a 10.1007/978-1-60761-759-4
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Cancer Susceptibility :
|b Methods and Protocols /
|c edited by Michelle Webb.
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| 250 |
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|a 1st ed. 2010.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2010.
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| 300 |
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|a XI, 295 p. 40 illus., 3 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 653
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| 505 |
0 |
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|a Identifying Cancer Susceptibility Genes -- The Identification of Colon Cancer Susceptibility Genes by Using Genome-Wide Scans -- Prioritizing Candidate Genetic Modifiers of BRCA1 and BRCA2 Using a Combinatorial Analysis of Global Expression and Polymorphism Association Studies of Breast Cancer -- Microarray-Based Comparative Genomic Hybridization (Array-CGH) as a Useful Tool for Identifying Genes Involved in Glioblastoma (GB) -- Multiplex Amplifiable Probe Hybridization (MAPH) Methodology as an Alternative to Comparative Genomic Hybridization (CGH) -- Utilizing Saccharomyces Cerevisiae to Identify Aneuploidy and Cancer Susceptibility Genes -- Computational Identification of Cancer Susceptibility Loci -- Digital Candidate Gene Approach (DigiCGA) for Identification of Cancer Genes -- Screening Cancer Susceptibility Genes -- The Use of Denaturing High Performance Liquid Chromatography (DHPLC) for Mutation Scanning of Hereditary Cancer Genes -- Enhanced Mismatch Mutation Analysis: Simultaneous Detection of Point Mutations and Large Scale Rearrangements by Capillary Electrophoresis, Application to BRCA1 and BRCA2 -- Economical Protocol for Combined Single-Strand Conformation Polymorphism and Heteroduplex Analysis on a Standard Capillary Electrophoresis Apparatus -- Mutational Screening of hMLH1 and hMSH2 that Confer Inherited Colorectal Cancer Susceptibility Using Denature Gradient Gel Electrophoresis (DGGE) -- s-RT-MELT: A Novel Technology for Mutation Screening -- Zoom-In Array Comparative Genomic Hybridization (aCGH) to Detect Germline Rearrangements in Cancer Susceptibility Genes -- Development of a Scoring System to Screen for BRCA1/2 Mutations -- Use of Splicing Reporter Minigene Assay to Evaluate the Effect on Splicing of Unclassified Genetic Variants -- Functional Analysis of Human BRCA2 Variants Using a Mouse Embryonic Stem Cell-Based Assay -- Developing Functional Assays for BRCA1 Unclassified Variants.
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| 650 |
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0 |
|a Oncology .
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| 650 |
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|a Cancer research.
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| 650 |
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|a Human genetics.
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| 650 |
1 |
4 |
|a Oncology.
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| 650 |
2 |
4 |
|a Cancer Research.
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| 650 |
2 |
4 |
|a Human Genetics.
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| 700 |
1 |
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|a Webb, Michelle.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
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