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150124s2015 xxu| s |||| 0|eng d |
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|a 9781493922697
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| 024 |
7 |
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|a 10.1007/978-1-4939-2269-7
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a Chemical Biology :
|b Methods and Protocols /
|c edited by Jonathan E. Hempel, Charles H. Williams, Charles C. Hong.
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| 250 |
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|a 1st ed. 2015.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2015.
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| 300 |
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|a XIV, 333 p. 65 illus., 40 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1263
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| 505 |
0 |
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|a Identification of Therapeutic Small Molecule Leads in Cultured Cells Using Multiplexed Pathway Reporter Read-outs -- Applying the Logic of Genetic Interaction to Discover Small Molecules That Functionally Interact with Human Disease Alleles -- Construction and Application of a Photo-cross-linked Chemical Array -- High Content Screening for Modulators of Cardiac Differentiation in Human Pluripotent Stem Cells -- Small Molecule High-Throughput Screening Utilizing Xenopus Egg Extract -- Fission Yeast-based High-throughput Screens for PKA Pathway Inhibitors and Activators -- A Method for High-throughput Analysis of Chronological Aging in Schizosaccharomyces pombe -- Protocols for the Routine Screening of Drug Sensitivity in the Human Parasite Trichomonas vaginalis -- Chemical Genetic Screens Using Arabidopsis thaliana Seedlings Grown on Solid Medium -- Small Molecule Screening Using Drosophila Models of Human Neurological Disorders -- High-throughput Small Molecule Screening in Caenorhabditis elegans -- Whole-organism Screening for Modulators of Fasting Metabolism Using Transgenic Zebrafish -- High Content Screening for Modulators of Cardiovascular or Global Developmental Pathways in Zebrafish -- Extraction Methods of Natural Products from Traditional Chinese Medicines -- Bioassay-guided Identification of Bioactive Molecules from Traditional Chinese Medicines -- NMR Screening in Fragment-Based Drug Design: A Practical Guide -- Practical Strategies for Small Molecule Probe Development in Chemical Biology -- Principal Component Analysis as a Tool for Library Design: A Case Study Investigating Natural Products, Brand-name Drugs, Natural Product-like Libraries, and Drug-like Libraries -- Small Molecule Library Screening by Docking with PyRx -- Fluorous Photoaffinity Labeling to Probe Protein-Small Molecule Interactions -- Identification of the Targets of Biologically Active Small Molecules Using Quantitative Proteomics -- Drug Affinity Responsive Target Stability (DARTS) for Small Molecule Target Identification -- Chemical Genomic Profiling via Barcode Sequencing to Predict Compound Mode of Action -- Image-Based Prediction of Drug Target in Yeast.
|
| 650 |
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0 |
|a Biochemistry.
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| 650 |
1 |
4 |
|a Biochemistry, general.
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| 700 |
1 |
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|a Hempel, Jonathan E.
|e editor.
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| 700 |
1 |
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|a Williams, Charles H.
|e editor.
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| 700 |
1 |
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|a Hong, Charles C.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
|