Chemosensitivity : Volume II: In Vivo Models, Imaging, and Molecular Regulators /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Blumenthal, Rosalyn D. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2005.
Edición:1st ed. 2005.
Colección:Methods in Molecular Medicine, 111
Materias:
Tabla de Contenidos:
  • Measurements of DNA Damage, Cell Death, and Regulators of Cytotoxicity
  • In Vitro Micronucleus Technique to Predict Chemosensitivity
  • Cell Cycle and Drug Sensitivity
  • TUNEL Assay as a Measure of Chemotherapy-Induced Apoptosis
  • Apoptosis Assessment by the DNA Diffusion Assay
  • PARP Cleavage and Caspase Activity to Assess Chemosensitivity
  • Diphenylamine Assay of DNA Fragmentation for Chemosensitivity Testing
  • Immunodetecting Members of the Bcl-2 Family of Proteins
  • Correlation of Telomerase Activity and Telomere Length to Chemosensitivity
  • Application of Silicon Sensor Technologies to Tumor Tissue In Vitro
  • Overview of Tumor Cell Chemoresistance Mechanisms
  • Flow Cytometric Monitoring of Fluorescent Drug Retention and Efflux
  • Flow Cytometric Measurement of Functional and Phenotypic P-Glycoprotein
  • Measurement of Ceramide and Sphingolipid Metabolism in Tumors
  • Genomics, Proteomics, and Chemosensitivity
  • Gene Expression Profiling to Characterize Anticancer Drug Sensitivity
  • Identifying Genes Related to Chemosensitivity Using Support Vector Machine
  • Genetic Manipulation of Yeast to Identify Genes Involved in Regulation of Chemosensitivity
  • Real-Time RT-PCR (Taqman®) of Tumor mRNA to Predict Sensitivity of Specimens to 5-Fluorouracil
  • Use of Proteomics to Study Chemosensitivity
  • In VIVO Animal Modeling of Chemosensitivity
  • Clinically Relevant Metastatic Breast Cancer Models to Study Chemosensitivity
  • Orthotopic Metastatic (MetaMouse®) Models for Discovery and Development of Novel Chemotherapy
  • Preclinical Testing of Antileukemic Drugs Using an In Vivo Model of Systemic Disease
  • Assessing Growth and Response to Therapy in Murine Tumor Models
  • Evaluation of Chemosensitivity of Micrometastases with Green Fluorescent Protein Gene-Tagged Tumor Models in Mice
  • 99mTc-Annexin A5 Uptake and Imaging to Monitor Chemosensitivity
  • Magnetic Resonance Imaging of Tumor Response to Chemotherapy
  • Metabolic Monitoring of Chemosensitivity with 18FDG PET.