Chromothripsis : Methods and Protocols /

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Pellestor, Franck. (Editor)
Format: eBook
Language:English
Published: New York, NY : Springer New York : Imprint: Humana, 2018.
Edition:1st ed. 2018.
Series:Methods in Molecular Biology, 1769
Subjects:
Table of Contents:
  • The Genomic Characteristics and Origin of Chromothripsis
  • Clinical Consequences of Chromothripsis and Other Catastrophic Cellular Events
  • Potential Role of Chromothripsis in the Genesis of Complex Chromosomal Rearrangements in Human Gametes and Preimplantation Embryo
  • Chromothripsis and the Macroevolution Theory
  • Analysis of Chromothripsis by Combined FISH and Microarray Analysis
  • Chromothripsis Detectable in Small Supernumerary Marker Chromosomes (sSMC) Using Fluorescence In Situ Hybridization (FISH)
  • Identification of Chromothripsis in Biopsy Using SNP-Based Microarray
  • Detection of Chromothripsis in Plants
  • RNA-Seq Analysis to Detect Abnormal Fusion Transcripts Linked to Chromothripsis
  • Experimental Determination of Checkpoint Adaptation by Mitotic Shake-Off and Microscopy
  • A Role for Retrotransposons in Chromothripsis
  • Generation of Micronuclei and Detection of Chromosome Pulverization
  • Detection of Impaired DNA Replication and Repair in Micronuclei as Indicators of Genomic Instability and Chromothripsis
  • Study of Telomere Dysfunction in TP53 Mutant LoVo Cell Lines as a Model for Genomic Instability
  • Genes, Proteins, and Biological Pathways Preventing Chromothripsis
  • Expression of Genes Associated with Telomere Homeostasis in TP53 Mutant LoVo Cell Lines as a Model for Genomic Instability
  • Chromothripsis Detection and Characterization Using the CTLPScanner Web Server
  • ChromothripsisDB: A Curated Database for the Documentation, Visualization, and Mining of Chromothripsis Data
  • Time-Lapse Imaging for the Detection of Chromosomal Abnormalities in Primate Pre-Implantation Embryos
  • Correlative Live Imaging and Immunofluorescence for Analysis of Chromosome Segregation in Mouse Preimplantation Embryos
  • Experimental Induction of Genome Chaos
  • Looking for Broken TAD Boundaries and Changes on DNA Interactions: Clinical Guide to 3D Chromatin Changes Analysis in Complex Chromosomal Rearrangements and Chromothripsis.