Biocombinatorial Approaches for Drug Finding /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Wohlleben, W. (Editor ), Spellig, T. (Editor ), Müller-Tiemann, B. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2005.
Edición:1st ed. 2005.
Colección:Ernst Schering Foundation Symposium Proceedings, 51
Materias:
Tabla de Contenidos:
  • Protein Domain Fold Similarity and Natural Product Structure as Guiding Principles for Compound Library Design
  • Sources of Polyketides and Non-Ribosomal Peptides
  • Polyketide Synthases: Mechanisms and Models
  • Functional and Structural Basis for Targeted Modification of Non-Ribosomal Peptlde Synthetases
  • Prerequisites for Combinatorial Biosynthesis: Evolution of Hybrid NRPS/PKS Gene Clusters
  • Engineering Glycosylation in Bioactive Compounds by Combinatorial Biosynthesis
  • Glycosyltransferases and Other Tailoring Enzymes as Tools for the Generation of Novel Compounds
  • Enzymatic Incorporation of Halogen Atoms into Natural Compounds
  • From Glucose to Antibiotics: What Controls the Fluxes?
  • Precursor-Directed Biosynthesis for the Generation of Novel Glycopetides
  • Tool-Box: Tailoring Enzymes for Bio-Combinatorial Lead Development and as Markers for Genome-Based Natural Product Lead Discovery
  • Natural Product Biosynthetic Assembly Lines: Prospects and Challenges for Reprogramming.