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02215nam a22002895i 4500 |
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20200929150608.0 |
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cr nn 008mamaa |
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181017s2018 xxu| s |||| 0|eng d |
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|a 9781493986392
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| 024 |
7 |
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|a 10.1007/978-1-4939-8639-2
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a Computational Chemogenomics /
|c edited by J.B. Brown.
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| 250 |
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|a 1st ed. 2018.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2018.
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| 300 |
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|a XII, 454 p. 201 illus., 147 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1825
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| 505 |
0 |
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|a A Survey of Web-Based Chemogenomic Data Resources -- Finding Potential Multi-Target Ligands Using PubChem -- Fundamental Bioinformatic and Chemoinformatic Data Processing -- Parsing Compound-Protein Bioactivity Tables -- Impact of Molecular Descriptors on Computational Models -- Physicochemical Property Labels as Molecular Descriptors for Improved Analysis of Compound-Protein and Compound-Compound Networks -- Core Statistical Methods for Chemogenomic Data -- Structure-Based Detection of Orthosteric and Allosteric Pockets at Protein-Protein Interfaces -- Single Binding Pockets versus Allosteric Binding -- Mapping Biological Activities to Different Types of Molecular Scaffolds: Exemplary Application to Protein Kinase Inhibitors -- SAR Matrix Method for Large-Scale Analysis of Compound Structure-Activity Relationships and Exploration of Multi-Target Activity Spaces -- Linear and Kernel Model Construction Methods for Predicting Drug-Target Interactions in a Chemogenomic Framework -- Selection of Informative Examples in Chemogenomic Datasets -- A Platform for Comprehensive Genomic Profiling in Human Cancers and Pharmacogenomics Therapy Selection -- The Future of Computational Chemogenomics.
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| 650 |
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|a Bioinformatics.
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| 650 |
1 |
4 |
|a Bioinformatics.
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| 700 |
1 |
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|a Brown, J.B.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
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