Disease Gene Identification : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: DiStefano, Johanna K. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2011.
Edición:1st ed. 2011.
Colección:Methods in Molecular Biology, 700
Materias:
Tabla de Contenidos:
  • Technological Issues and Experimental Design of Gene Association Studies
  • Statistical Issues in Gene Association Studies
  • Identification of Causal Sequence Variants of Disease in the Next Generation Sequencing Era
  • Microarray-Based Genome-Wide Association Studies Using Pooled DNA
  • Medium-Throughput SNP Genotyping Using Mass Spectrometry: Multiplex SNP Genotyping Using the iPLEX® Gold Assay
  • Targeted SNP Genotyping Using the TaqMan Assay
  • Bar-Coded, Multiplexed Sequencing of Targeted DNA Regions Using the Illumina Genome Analyzer
  • Site-Directed Mutagenesis
  • Gene Expression Profiling of Tissues and Cell Lines: A Dual Color Microarray Method
  • Methods for microRNA Microarray Profiling
  • Allelic Expression Profiling to Dissect Genome-Wide Association Study Signals
  • Quantitative Polymerase Chain Reaction: Quantitative PCR Using the Comparative Cq Method
  • Genomic Analysis by Oligonucleotide Array Comparative Genomic Hybridization Utilizing Formalin-Fixed Paraffin Embedded Tissues
  • RNA Mapping Protocols: Northern-Blot and Amplification of cDNA Ends
  • High Content RNA Interference Assay: Analysis of Tau Hyperphosphorylation as a Generic Paradigm
  • Integrative Systems Biology Approaches to Identify and Prioritize Disease and Drug Candidate Genes
  • Identification of a Common Variant Affecting Human Episodic Memory Performance Using a Pooled Genome-Wide Association Approach: A Case Study of Disease Gene Identification
  • RNAi-Based Functional Pharmacogenomics
  • Genetic Predisposition to β-Thalassemia and Sickle Cell Anemia in Turkey: A Molecular Diagnostic Approach.