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03323nam a22003615i 4500 |
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000280604 |
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20211029082856.0 |
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cr nn 008mamaa |
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100301s2008 xxu| s |||| 0|eng d |
| 020 |
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|a 9780387749013
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| 024 |
7 |
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|a 10.1007/978-0-387-74901-3
|2 doi
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| 040 |
|
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
|
| 245 |
1 |
0 |
|a Drug Absorption Studies :
|b In Situ, In Vitro and In Silico Models /
|c edited by Carsten Ehrhardt, Kwang-Jin Kim.
|
| 250 |
|
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|a 1st ed. 2008.
|
| 260 |
# |
# |
|a New York, NY :
|b Springer US :
|b Imprint: Springer,
|c 2008.
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| 300 |
|
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|a XXII, 696 p. :
|b online resource.
|
| 336 |
|
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Biotechnology: Pharmaceutical Aspects ;
|v VII
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| 505 |
0 |
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|a Perfused Organ Level/In Situ Techniques -- Models for Skin Absorption and Skin Toxicity Testing -- Models of the Small Intestine -- Drug Absorption from the Colon In Situ -- In Vivo and In Vitro Models for Assessing Drug Absorption Across the Buccal Mucosa -- In Situ and Ex Vivo Nasal Models for Preclinical Drug Development Studies -- The Isolated Perfused Lung for Drug Absorption Studies -- Cellular Level—In Vitro Models of Epithelial and Endothelial Barriers -- In Vitro Models for Investigations of Buccal Drug Permeation and Metabolism -- In Vitro Screening Models to Assess Intestinal Drug Absorption and Metabolism -- In Vitro Cellular Models for Nasal Drug Absorption Studies -- In Vitro Models of the Tracheo-Bronchial Epithelium -- In Vitro Models of the Alveolar Epithelial Barrier -- Cell Culture Models of the Corneal Epithelium and Reconstructed Cornea Equivalents for In Vitro Drug Absorption Studies -- The Conjunctival Barrier in Ocular Drug Delivery -- Inner Blood—Retinal Barrier: Transport Biology and Methodology -- Regulation of Paracellular Permeability in Low-Resistance Human Vaginal-Cervical Epithelia -- In Vitro Models and Multidrug Resistance Mechanisms of the Placental Barrier -- In Vitro Models to Study Blood-Brain Barrier Function -- High-Throughput Screening Using Caco-2 Cell and PAMPA Systems -- Instrumented In Vitro Approaches to Assess Epithelial Permeability of Drugs from Pharmaceutical Formulations -- Bioinformatics—In Silico Tools to Predict Drug Absorption -- Modeling Transdermal Absorption -- Physiologically Based in Silico Models for the Prediction of Oral Drug Absorption -- In Silico Modeling for Blood—Brain Barrier Permeability Predictions -- Molecular/Sub-Cellular Level—Mechanistic Tools -- Impact of Drug Transport Proteins -- Cloning and Functional Heterologous Expression of Transporters -- The Pharmacology of Caveolae -- Immortalization Strategies for Epithelial Cells in Primary Culture -- Binding-Uptake Studies and Cellular Targeting -- Regulatory Considerations -- Drug Permeability Studies in Regulatory Biowaiver Applications.
|
| 650 |
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0 |
|a Pharmacology.
|
| 650 |
|
0 |
|a Biotechnology.
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| 650 |
|
0 |
|a Cell biology.
|
| 650 |
|
0 |
|a Medicine.
|
| 650 |
1 |
4 |
|a Pharmacology/Toxicology.
|
| 650 |
2 |
4 |
|a Biotechnology.
|
| 650 |
2 |
4 |
|a Cell Biology.
|
| 650 |
2 |
4 |
|a Medicine/Public Health, general.
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| 700 |
1 |
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|a Ehrhardt, Carsten.
|e editor.
|
| 700 |
1 |
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|a Kim, Kwang-Jin.
|e editor.
|
| 710 |
2 |
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|a SpringerLink (Online service)
|
| 773 |
0 |
|
|t Springer eBooks
|