DNA Methyltransferases - Role and Function /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Jeltsch, Albert. (Editor ), Jurkowska, Renata Z. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2016.
Edición:1st ed. 2016.
Colección:Advances in Experimental Medicine and Biology, 945
Materias:
Tabla de Contenidos:
  • Mechanisms and biological roles of DNA methylation and DNA methyltransferases – from past achievements to future challenges
  • DNA and RNA pyrimidine nucleobase alkylation at the carbon-5 position
  • Bacterial DNA methylation and methylomes
  • Domain structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA methyltransferases
  • Enzymology of mammalian DNA methyltransferases
  • Genetic studies on mammalian DNA methyltransferases
  • The role of DNA methylation in cancer
  • Structure and mechanism of plant DNA methyltransferases
  • DNA methylation and gene regulation in honey bees: from genome-wide analyses to obligatory epi-alleles
  • N6-methyladenine: a conserved and dynamic DNA mark
  • Pathways of DNA demethylation
  • Structure and function of TET enzymes
  • Proteins that read DNA methylation
  • DNA base flipping – a general mechanism for writing, reading, and erasing DNA modifications
  • Current and emerging technologies for the analysis of the genome-wide and locus-specific DNA methylation patterns
  • DNA methyltransferase inhibitors – development and applications
  • Rewriting DNA methylation signatures at will: the curable genome within reach?
  • Engineering and directed evolution of DNA methyltransferases
  • DNA labeling using DNA methyltransferases.