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100715s2010 xxu| s |||| 0|eng d |
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|a 9781597453639
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| 024 |
7 |
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|a 10.1007/978-1-59745-363-9
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a G-Quadruplex DNA :
|b Methods and Protocols /
|c edited by Peter Baumann.
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| 250 |
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|a 1st ed. 2010.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2010.
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| 300 |
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|a XII, 276 p. 65 illus., 2 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 608
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| 505 |
0 |
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|a G-Quadruplexes: From Guanine Gels to Chemotherapeutics -- Molecular Modeling and Simulation of G-Quadruplexes and Quadruplex-Ligand Complexes -- Computational Approaches to the Detection and Analysis of Sequences with Intramolecular G-Quadruplex Forming Potential -- Preparation of G-Quartet Structures and Detection by Native Gel Electrophoresis -- Biochemical Techniques for the Characterization of G-Quadruplex Structures: EMSA, DMS Footprinting, and DNA Polymerase Stop Assay -- Real-Time Observation of G-Quadruplex Dynamics Using Single-Molecule FRET Microscopy -- Sedimentation Velocity Ultracentrifugation Analysis for Hydrodynamic Characterization of G-Quadruplex Structures -- 2-Aminopurine as a Probe for Quadruplex Loop Structures -- Assessing DNA Structures with 125I Radioprobing -- Monitoring the Temperature Unfolding of G-Quadruplexes by UV and Circular Dichroism Spectroscopies and Calorimetry Techniques -- Probing Telomeric G-Quadruplex DNA Structures in Cells with In Vitro Generated Single-Chain Antibody Fragments -- Detection of G-Quadruplexes in Cells and Investigation of G-Quadruplex Structure of d(T2AG3)4 in K+ Solution by a Carbazole Derivative: BMVC -- Isolation of G-Quadruplex DNA Using NMM-Sepharose Affinity Chromatography -- Quantifying Interactions Between G-Quadruplex DNA and Transition-Metal Complexes -- G4-FID: A Fluorescent DNA Probe Displacement Assay for Rapid Evaluation of Quadruplex Ligands.
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| 650 |
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0 |
|a Biochemistry.
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| 650 |
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0 |
|a Cell biology.
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| 650 |
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0 |
|a Human genetics.
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| 650 |
1 |
4 |
|a Biochemistry, general.
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| 650 |
2 |
4 |
|a Cell Biology.
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| 650 |
2 |
4 |
|a Human Genetics.
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| 700 |
1 |
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|a Baumann, Peter.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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