Gene Therapy for HIV : From Inception to a Possible Cure /
| Autores principales: | , |
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| Autor Corporativo: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
New York, NY :
Springer New York : Imprint: Springer,
2014.
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| Edición: | 1st ed. 2014. |
| Colección: | SpringerBriefs in Biochemistry and Molecular Biology,
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| Materias: |
Tabla de Contenidos:
- Principles of Gene Therapy
- Injection of Naked DNA
- Non-Viral Gene Transfer (Transfection) Methods
- Viral gene transfer (transduction) methods
- Retroviruses
- Other viruses.- History of Gene Therapy.- Principles of HIV Gene Therapy.- Gene Therapy Vectors.- Lentiviral vectors.- Other modifications and additions.- Anti-HIV genes.- RNA-strategies.- Vector production.- Stem Cells for HIV Gene Therapy.- Pluripotent stem cells.- Animal Models Used in HIV Gene Therapy
- Murine models.- HIV infections in humanized mice.- Non-human primates.- Manufacturing of a GMP grade product for HIV gene therapy.- Clinical applications of HIV gene therapy.- Clinical trials of T cell gene therapy.- Stem cell gene therapy clinical trials for HIV.- Is A Cure for HIV Possible?.