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160419s2016 xxu| s |||| 0|eng d |
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|a 9781493935697
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| 024 |
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|a 10.1007/978-1-4939-3569-7
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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|a Computational Design of Ligand Binding Proteins /
|c edited by Barry L. Stoddard.
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| 250 |
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|a 1st ed. 2016.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2016.
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| 300 |
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|a XVI, 375 p. 94 illus., 76 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a Methods in Molecular Biology,
|v 1414
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| 505 |
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|a In silico Identification and Characterization of Protein-Ligand Binding Sites -- Computational Modeling of Small Molecule Ligand Binding Interactions and Affinities -- Binding Site Prediction of Proteins with Organic Compounds or Peptides Using GALAXY Web Servers -- Rosetta and the Design of Ligand Binding Sites -- PocketOptimizer and the Design of Ligand Binding Sites -- Proteus and the Design of Ligand Binding Sites -- A Structure Based Design Protocol for Optimizing Combinatorial Protein Libraries -- Combined and Iterative Use of Computational Design and Directed Evolution for Protein-Ligand Binding Design -- Improving Binding Affinity and Selectivity of Computationally Designed Ligand Binding Proteins Using Experiments -- Computational Design of Multinuclear Metalloproteins Using Unnatural Amino Acids -- De Novo Design of Metalloproteins and Metalloenzymes in a Three-helix Bundle -- Design of Light-Controlled Protein Conformations and Functions -- Computational Introduction of Catalytic Activity into Proteins -- Generating High Accuracy Peptide Binding Data in High Throughput with Yeast Surface Display and SORTCERY -- Design of Specific Peptide-Protein Recognition -- Computational Design of DNA-binding Proteins -- Motif-driven Design of Protein-Protein Interfaces -- Computational Reprogramming of T Cell Antigen Receptor Binding Properties -- Computational Modeling of T Cell Receptor Complexes -- Computational Design of Protein Linkers -- Modeling of Protein-RNA Complex Structures Using Computational Docking Methods.
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| 650 |
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|a Proteins .
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| 650 |
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|a Protein Science.
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| 650 |
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|a Protein-Ligand Interactions.
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| 700 |
1 |
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|a Stoddard, Barry L.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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