Fifty Years of Cytochrome P450 Research /
| Autor Corporativo: | |
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| Otros Autores: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Tokyo :
Springer Japan : Imprint: Springer,
2014.
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| Edición: | 1st ed. 2014. |
| Materias: |
Tabla de Contenidos:
- Preface
- Part 1 Cytochrome P450 History
- 1 Pioneers in the Early Years of Cytochrome P450 Research
- 2 Fifty Years of Progress in Drug Metabolism and Toxicology: What Do We Still Need to Know About Cytochrome P450 Enzymes?
- 3 Fifty Years of Cytochrome P450 Research: Examples of What We Know and Don't Know
- Part 2 Structure, Function, and Practical Applications of P450
- 4 Cytochrome P450 Dynamics
- 5 Structural and Functional Diversity of Cytochrome P450
- 6 Oxygenation of Non native Substrates Using a Malfunction State of Cytochrome P450s
- 7 Plant Cytochrome P450s in Triterpenoid Biosynthesis: Diversity and Application to Combinatorial Biosynthesis
- 8 Mammalian and Bacterial Cytochromes P450 Involved in Steroid Hydroxylation: Regulation of Catalysis and Selectivity and Potential Applications
- 9 Neurosteroids: Regional Steroidogenesis
- 10 Whole Cell-Dependent Biosynthesis of Drug Metabolites Using Genetically Engineered Budding Yeast
- 11 Metabolic Diversity and Cytochromes P450 of Fungi
- 12 Metabolic Engineering of Flower Colour Pathways Using Cytochromes P450
- Part 3 Gene Regulation of P450
- 13 Aryl Hydrocarbon Receptor Suppresses Cecal Carcinogenesis
- 14 Epidermal Growth Factor Receptor: The Phenobarbital Receptor That Elicits CAR Activation Signal for P450 Induction
- 15 Steroidogenic Cytochrome P450 Gene CYP11A1: Functions and Regulation
- 16 Cooperative Regulation of Expression of Cytochrome P450 Enzymes by Aryl Hydrocarbon Receptor and Vitamin D Receptor
- Part 4 Drug Metabolism
- 17 Species, Ethnic and Individual Differences in Human Drug-Metabolizing Cytochrome P450 Enzymes
- 18 Cytochrome P450-Depedent Change in UDP- Glucuronosyltransferase Function and Its Reverse Regulation
- 19 Control of Xeno/Endobiotics-Metabolizing Cytochrome P450s by Micro RNAs
- 20 The Pharmacogenomics of Cytochrome P450s: From Molecular to Clinical Application
- 21 Cytochrome P450 Polymorphisms of Clinical Importance
- BM Epilogue
- Index.