Erythropoietins, Erythropoietic Factors, and Erythropoiesis : Molecular, Cellular, Preclinical, and Clinical Biology /
| Autor Corporativo: | |
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| Otros Autores: | , , |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Basel :
Birkhäuser Basel : Imprint: Birkhäuser,
2009.
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| Edición: | 2nd ed. 2009. |
| Colección: | Milestones in Drug Therapy,
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| Materias: |
Tabla de Contenidos:
- Background
- Erythropoiesis: an overview
- Regulation of endogenous erythropoietin production
- Biology of erythropoietin
- Erythropoiesis-genetic abnormalities
- Erythropoiesis-stimulating agents
- Studies of erythropoiesis and the discovery and cloning of recombinant human erythropoietin
- Commercial production of recombinant erythropoietins
- Biosimilar epoetins
- New molecules and formulations
- Erythropoietin receptor
- Structural basis for the signal transduction of erythropoietin
- Intracellular signaling by the erythropoietin receptor
- Mechanism of erythropoietin receptor activation
- Clinical utility
- Pharmacokinetics of erythropoiesis-stimulating agents
- Use of erythropoietic stimulating agents in the setting of renal disease
- Abuse of recombinant erythropoietins and blood products by athletes
- Role and regulation of iron metabolism in erythropoiesis and disease
- Nonhematopoietic effects of erythropoiesis-stimulating agents.