Fragment-Based Methods in Drug Discovery /
| Autor Corporativo: | |
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| Otros Autores: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
New York, NY :
Springer New York : Imprint: Humana,
2015.
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| Edición: | 1st ed. 2015. |
| Colección: | Methods in Molecular Biology,
1289 |
| Materias: |
Tabla de Contenidos:
- Solvation Methods for Protein-Ligand Docking
- Binding Site Druggability Assessment in Fragment-Based Drug Design
- Generating "Fragment-Based Virtual Library" Using Pocket Similarity Search of Ligand-Receptor Complexes
- Virtual Fragment Preparation for Computational Fragment-Based Drug Design
- Fragment Library Design: Using Cheminformatics and Expert Chemists to Fill Gaps in Existing Fragment Libraries
- Protocol for Fragment Hopping
- Site Identification by Ligand Competitive Saturation (SILCS) Simulations for Fragment-Based Drug Design
- A Computational Fragment-Based De Novo Design Protocol Guided by Ligand Efficiency Indices (LEI)
- Scoring Functions for Fragment-Based Drug Discovery
- Computational Methods for Fragment-Based Ligand Design: Growing and Linking
- Design Strategies for Computational Fragment-Based Drug Design
- Protein Binding Site Analysis for Drug Discovery Using a Computational Fragment-Based Method
- Fragment-Based Design of Kinase Inhibitors: A Practical Guide
- Designing a Small Molecule Erythropoietin Mimetic
- Designing an Orally Available Non-Toxic p38 Inhibitor with a Fragment-Based Strategy.