Drug Design and Discovery : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Satyanarayanajois, Seetharama D. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2011.
Edición:1st ed. 2011.
Colección:Methods in Molecular Biology, 716
Materias:
Tabla de Contenidos:
  • Virtual Screening for Lead Discovery
  • Computer-Aided Drug Discovery and Development
  • Using Active Site Mapping and Receptor-Based Pharmacophore Tools: Prelude to Docking and De Novo/Fragment-Based Ligand Design
  • Methods for Evaluation of Structural and Biological Properties of Anti-Invasive Natural Products
  • Solid-Phase Peptide Synthesis Using Microwave Irradiation
  • Fluorescent and Lanthanide Labeling for Ligand Screens, Assays, and Imaging
  • DNA-Directed Assembly Microarray for Protein and Small Molecule Inhibitor Screening
  • Selection of Peptide Ligands for Human Placental Transcytosis Systems Using In vitro Phage Display
  • Optimization of the Tetrazolium Dye (MTT) Colorimetric Assay for Cellular Growth and Viability
  • Imaging NF- κB Signaling in Mice for Screening Anti-Cancer Drugs
  • Evaluation of Anticancer Agents Using Flow Cytometry Analysis of Cancer Stem Cells
  • Chemical Screening with Zebrafish Embryos.- iTRAQTM Labeling Coupled with LC-MALDI Mass Spectrometry for Monitoring Temporal Response of Colorectal Cancer Cells to Butyrate Treatment
  • Heterotypic Cell Adhesion Assay for the Study of Cell Adhesion Inhibition
  • Evaluation of Antibacterial Activity of Proteins and Peptides Using a Specific Animal Model for Wound Healing
  • In vitro Immunogenicity Risk Assessment of Therapeutic Proteins in Preclinical Setting.