Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics /
| Corporate Author: | |
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| Other Authors: | , |
| Format: | eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2013.
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| Edition: | 1st ed. 2013. |
| Subjects: |
Table of Contents:
- Brief historical account of HBOC development
- Physiology of respiration
- Oxygen transport to tissues
- Pathophysiology of acute anemia
- Global blood safety and need for safe blood supply
- Blood transfusion and its limitations
- Scientific basis and design of HBOCs
- HBOCs: a regulatory perspective
- Current HBOC products in development
- Clinical indications and clinical trials of HBOCs
- HBOCs and adverse events observed in clinical trials
- HBOC-mediated vasoactivity and hypertension
- HBOC and oxygen and nitrogen radical mediated toxicity
- HBOCs and clinical laboratory interference
- Animal models for HBOC studies
- New emerging Technologies for universal RBCs
- Future prospects.