Heterologous Protein Production in CHO Cells : Methods and Protocols /

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Meleady, Paula. (Editor)
Format: eBook
Language:English
Published: New York, NY : Springer New York : Imprint: Humana, 2017.
Edition:1st ed. 2017.
Series:Methods in Molecular Biology, 1603
Subjects:
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024 7 |a 10.1007/978-1-4939-6972-2  |2 doi 
040 |a Sistema de Bibliotecas del Tecnológico de Costa Rica 
245 1 0 |a Heterologous Protein Production in CHO Cells :  |b Methods and Protocols /  |c edited by Paula Meleady. 
250 |a 1st ed. 2017. 
260 # # |a New York, NY :  |b Springer New York :  |b Imprint: Humana,  |c 2017. 
300 |a X, 252 p. 35 illus., 28 illus. in color. :  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Methods in Molecular Biology,  |v 1603 
505 0 |a Strategies and Considerations for Improving Expression of 'Difficult to Express' Proteins in CHO Cells -- Glycoengineering of CHO Cells to Improve Product Quality -- Large-Scale Transient Transfection of Chinese Hamster Ovary Cells in Suspension -- Cloning of Single-Chain Antibody Variants by Overlap-Extension PCR for Evaluation of Antibody Expression in Transient Gene Expression -- Anti-Apoptosis Engineering for Improved Protein Production from CHO Cells -- Conditional Knockdown of Endogenous MicroRNAs in CHO Cells using TET-ON-SanDI Sponge Vectors -- Application of CRISPR/Cas9 Genome Editing to Improve Recombinant Protein Production in CHO Cells -- Improved CHO Cell Line Stability and Recombinant Protein Expression During Long-Term Culture -- Selection of High-Producing Clones using FACS for CHO Cell Line Development -- The 'Omics Revolution in CHO Biology: Roadmap to Improved CHO Productivity -- A Bioinformatics Pipeline for the Identification of CHO Cell Differential Gene Expression from RNA-Seq Data -- Filter-Aided Sample Preparation (FASP) for Improved Proteome Analysis of Recombinant Chinese Hamster Ovary Cells -- Phosphopeptide Enrichment and LC-MS/MS Analysis to Study the Phosphoproteome of Recombinant Chinese Hamster Ovary Cells -- Engineer Medium and Feed for Modulating N-Glycosylation of Recombinant Protein Production in CHO Cell Culture -- Glycosylation Analysis of Therapeutic Glycoproteins Produced in CHO Cells -- Characterization of Host Cell Proteins (HCPs) in CHO Cell Bioprocesses. 
650 0 |a Proteins . 
650 1 4 |a Protein Science. 
700 1 |a Meleady, Paula.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks